Results 131 to 140 of about 7,769,754 (302)

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Treating planning flows in patient flows

, 2013
Het goed aansturen van zorgprocessen is van essentieel belang in de moderne gezondheidszorg. Dit proefschrift richt zich op het uitbreiden van het kennisbestand omtrent patiëntenstromen en logistieke besluitvorming in ziekenhuizen en draagt bij aan de literatuur op het raakvlak van zorgmanagement en operations management. In dit proefschrift richten we
openaire   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Patient Safety Commission: 2006 report to the Legislature

, 2006
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on Nov.

core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

A renal colic fast track pathway to improve waiting times and outcomes for patients presenting to the emergency department

Open Access Emergency Medicine, 2017
Omar Al Kadhi,1 Kate Manley,1 Madhavi Natarajan,1 Valmiki Lutchmedial,2 Abbi Forsyth,2 Kate Tabrett,2 Jonathan Betteridge,2 William Finch,3 Heinrich Hollis4 1Department of Urology, Norfolk and Norwich University Hospitals NHS Foundation Trust, 2Faculty ...
Al Kadhi O, Manley K, Natarajan M, Lutchmedial V, Forsyth A, Tabrett K, Betteridge J, Finch W, Hollis H   +8 more
doaj  

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Improving referral management processes in the Navigation Hub Patient Flow Admin Team

Project Aim: To improve the efficiency of the referral management processes within the Navigation Hub Patient Flow Admin Team. Inefficient referral management processes within the Navigation Hub administrative workload have the potential to cause delays,
Greenwood, Rachel, Supported by the Quality Improvement Team   +1 more
core  

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

PXJ Volume 12 – Key Theme Summary and Article Index

Volume 12 of the Patient Experience Journal showcases a global dedication to advancing human experience in healthcare, illuminating both existing challenges and crucial emerging practices. The content, spanning three issues, emphasizes that improving the
Journal, Patient Experience
core   +1 more source