Results 111 to 120 of about 7,769,754 (302)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

LENGTH OF STAY AMONG EMERGENCY DEPARTMENT PATIENTS AT A PRIVATE TERTIARY HOSPITAL IN SOUTHWESTERN NIGERIA: A 5-YEAR INSTITUTIONAL RETROSPECTIVE STUDY

Nigerian Frontline Medicine Journal
: Background: Length of Stay (LOS) is a key performance indicator in emergency department (ED), reflecting both efficiency and quality of care. While extensively studied in high-income countries, there is limited evidence from sub-Saharan Africa ...
Omosanya Olusegun Emmanuel, Daniel Adepoju, Akinmade Akinola, Odeigah Louis Okeibunor, Oladejo James Opeyemi, Tonfamoworio Williams Tonfamoworio   +5 more
doaj   +2 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Optimizing diagnostic and management pathways for patients with eosinophilia of unknown origin: a multidisciplinary protocol for urgent and non-urgent evaluation

Frontiers in Medicine
IntroductionPersistent eosinophilia of unknown cause is a key feature of numerous health disorders. These conditions present diagnostic and management challenges, often leading to delayed treatment, increased morbidity and mortality and unnecessary ...
Silvia Sánchez-Ramón, Gloria Candelas Rodríguez, Jesús Gimeno Hernández, María Luisa González Gutiérrez, Sissy Fiorella Medina Salazar, Manuel Méndez Bailón, Begoña Navas Elorza, Ángel Nieto Sánchez, Teresa Robledo Echarren, Santiago Rueda Esteban, Marcos Oliver Fragiel Saavedra, María Dolores Zamora Barrios, Cristina Martínez Prada, Celina Benavente Cuesta, Celia Pinedo Sierra, EOS Multidisciplinary Group   +15 more
doaj   +1 more source

Patient flow.

, 2017
Patient flow.
Julien Frandon (3839086), Emilie Chipon (3839080), Ivan Bricault (3839095), Pierre Durand (3839089), Alexandre Moreau-Gaudry (3839092), Anne-Sophie Silvent (3839098), Maud Médici (3839083)   +6 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Patient flow.

, 2019
Patient flow.
Johan Nilsson (364438), Maya Landenhed Smith (6804209), Bodil Andersson (700856), J. Gustav Smith (162179), Gustav Zar (6804206)   +4 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Patient flow.

, 2014
Patient flow.
Monde Muyoyeta (372849), Deborah Milimo (547623), Nathan Kapata (313492), Pragnya Maduskar (547622), Laurens Hogeweg (547625), Nkatya Kasese (392884), Bram van Ginneken (403147), Maureen Moyo (59109), Rosanna Spooner (547624), Helen Ayles (42807)   +9 more
core   +1 more source