Results 111 to 120 of about 2,326,510 (303)
Healthcare queueing models. [PDF]
Healthcare systems differ intrinsically from manufacturing systems. As such, they require a distinct modeling approach. In this article, we show how to construct a queueing model of a general class of healthcare systems.
Creemers, Stefan, Lambrecht, Marc
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Emergency and on-demand health care: modelling a large complex system
, 2004 This paper describes how system dynamics was used as a central part of a whole-system review of emergency and on-demand health care in Nottingham, England.
Forrester JW +5 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Inter-district flow transfers : health and economic impacts : a thesis presented in partial fulfilment of the requirements for the degree of Master of Business Studies in Economics at Massey University, Albany, New Zealand [PDF]
, 2018 As part of the introduction of the New Zealand Public Health and Disabilities Act in 2000, the introduction of the Population Based Funding Formula led to a change in the flow of funds for transfer patients.
Bruce-Brand, Bronwyn
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Modeling a healthcare system as a queueing network:The case of a Belgian hospital. [PDF]
The performance of health care systems in terms of patient flow times and utilization of critical resources can be assessed through queueing and simulation models.
Creemers, Stefan, Lambrecht, Marc
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Open Access Emergency Medicine, 2017 Omar Al Kadhi,1 Kate Manley,1 Madhavi Natarajan,1 Valmiki Lutchmedial,2 Abbi Forsyth,2 Kate Tabrett,2 Jonathan Betteridge,2 William Finch,3 Heinrich Hollis4 1Department of Urology, Norfolk and Norwich University Hospitals NHS Foundation Trust, 2Faculty ...
Al Kadhi O +8 more
doaj
TIPS and HCC: friends or foes ? [PDF]
, 2016 Portal hypertension and hepatocellular carcinoma [HCC] are major complications of liver cirrhosis and may coexist in the same patient. Transjugular intrahepatic portosystemic shunt [TIPS] is an effective treatment for recurrent variceal bleeding
DE SANTIS, Adriano
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