Results 51 to 60 of about 1,398,260 (307)

Arrival time pattern and waiting time distribution of patients in the emergency outpatient department of a tertiary level health care institution of North India

Journal of Emergencies, Trauma and Shock, 2014
Background: Emergency Department (ED) of tertiary health care institute in India is mostly overcrowded, over utilized and inappropriately staffed.
Yogesh Tiwari, Sonu Goel, Amarjeet Singh
doaj   +1 more source

Fractional Flow Reserve-Based Patient Risk Classification

Diagnostics, 2023
Cardiovascular diseases (CVDs) are a leading cause of death. If not treated in a timely manner, cardiovascular diseases can cause a plethora of major life complications that can include disability and a loss of the ability to work.
Marijana Stanojević Pirković, Ognjen Pavić, Filip Filipović, Igor Saveljić, Tijana Geroski, Themis Exarchos, Nenad Filipović   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Room for improvement: One third of Lynch syndrome patients presenting for genetic testing in a highly specialised centre in Stockholm already have cancer

Hereditary Cancer in Clinical Practice, 2021
Background Lynch syndrome is caused by germline mutations in the mismatch repair genes and is characterised by a familial accumulation of colorectal and other cancers.
Sophie Walton Bernstedt, Jan Björk, Kaisa Fritzell, Allan D. Spigelman, Erik Björck, Ann-Sofie Backman   +5 more
doaj   +1 more source

Retrobulbar blood flow in patients with cataract [PDF]

British Journal of Ophthalmology, 2006
To investigate retrobulbar haemodynamics in patients with cataract.Colour Doppler imaging of the ophthalmic artery was carried out on the eye scheduled for surgery in 30 patients with cataract and in one randomly selected eye of 100 healthy controls.
Grieshaber MC, Koçak I, Dubler B, Flammer J, Orgül S   +4 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Flow-chart of the patient cohort included in this study.

, 2019
Flow-chart of the patient cohort included in this study.
Oriana Nanni (16186), Cristina Bottin (840045), Bruna Scaggiante (6861860), Fabrizio Zanconati (840043), Fabiola Giudici (5633354), Elisabetta Petracci (4612102), Maurizio Pinamonti (6861857)   +6 more
core   +1 more source

Development of a Prospective Data Registry System for Non-muscle-Invasive Bladder Cancer Patients Incorporated in the Electronic Patient File System

Frontiers in Oncology, 2019
Purpose: To develop a prospective non-muscle-invasive bladder cancer (NMIBC) data registry by generating NMIBC-specific electronic case report forms (eCRFs) in our institution's electronic patient file system, and to report on the development and ...
Murat Akand, Murat Akand, Tim Muilwijk, Jan Cornelissen, Siska Van Bruwaene, Kathy Vander Eeckt, Frederic Baekelandt, Pieter Mattelaer, Raf Van Reusel, Ben Van Cleynenbreugel, Steven Joniau, Frank Van Der Aa   +11 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Analysing the emergency department patient journey: Discovery of bottlenecks to emergency department patient flow

, 2017
OBJECTIVE: Despite significant workflow reform to comply with the federally mandated National Emergency Access Target (NEAT), Australian public hospitals continue to face significant barriers in achieving good ED patient flow.
Khanna, Sankalp, Boyle, Justin, Lind, James, Good, Norm, Norm Good, Sankalp Khanna, Bell, Anthony, Anthony Bell, James Lind, Justin Boyle   +9 more
core   +1 more source