Results 61 to 70 of about 1,398,260 (307)

A Discrete Event Simulation of Patient Flow in an Assisted Reproduction Clinic With the Integration of a Smart Health Monitoring System

IEEE Access
In spite of continuous medical and technological advances, there are still treatments today, e.g., infertility treatments, that have not been addressed using remote monitoring due to the absence of reliable devices and smart health monitoring systems ...
Anastasiia Gorelova, Santiago Melia, Diana Gadzhimusieva   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Patient flow.

, 2016
Patient flow.
Berit Lilienthal Heitmann (519995), Mette Kildevæld Simonsen (848217), Jan Erik Henriksen (848219), Volkert Siersma (848218), Rasmus Køster-Rasmussen (723838), Niels de Fine Olivarius (575870)   +5 more
core   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Managing Patient Flow Across an Acute Tertiary Care Hospital Through A Centralised Coordination Hub: Technological and Cultural Change – A Case Study

Asia Pacific Journal of Health Management
Aim: A centralised Coordination Hub was implemented at a large tertiary health service in Queensland, Australia to address problems associated with a fragmented, reactive and manual approach to patient flow.
Rachael Smithson, Tracey Doherty, Andrew Fisher   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Inhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study. [PDF]

, 2015
BACKGROUND: Spiromax® is a novel dry-powder inhaler containing formulations of budesonide plus formoterol (BF). The device is intended to provide dose equivalence with enhanced user-friendliness compared to BF Turbuhaler® in asthma and chronic ...
Philip Chetcuti, Hosker, Harold, Chrystyn, Henry, Azouz, Wahida, Saralaya, Dinesh, Dinesh Saralaya, Chetcuti, Philip, Wahida Azouz, Henry Chrystyn, Harold Hosker   +9 more
core   +1 more source

Patient flow.

, 2022
Patient flow.
Torgeir Bruun Wyller (4237051), Hege Kersten (3902092), Marte Sofie Wang-Hansen (11919927), Jūratė Šaltytė Benth (9582242)   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source