Results 81 to 90 of about 440,904 (297)

Quality improvement of a community-engaged authorship system: lessons learned from the RECOVER initiative

BMC Health Services Research
Background Inclusion of patients, caregivers, and community members in scientific research should be essential for patient-centered care. Patients’ lived experiences can propose new areas of focus that may not have previously been considered, ensure that
Shari Esquenazi-Karonika, Patenne D. Mathews, Marion J. Wood, Praveen M. Mudumbi, Janelle Linton, Jasmine Briscoe, Elle Seibert, K. Coombs, Gregory Laynor, Stuart D. Katz, Alicia Chung   +10 more
doaj   +1 more source

Clinicians’ experience of providing care: a rapid review

BMC Health Services Research, 2020
Background Health care services internationally are refocussing care delivery towards patient centred, integrated care that utilises effective, efficient and innovative models of care to optimise patient outcomes and system sustainability.
Maha Pervaz Iqbal, Elizabeth Manias, Laurel Mimmo, Stephen Mears, Briony Jack, Liz Hay, Reema Harrison   +6 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

A User Survey Finds That a Hospital Library Literature Search Service Has a Direct Impact on Patient Care

Evidence Based Library and Information Practice, 2015
A Review of: Farrell, A., Mason, J. (2014). Evaluating the Impact of Literature Searching Services on Patient Care Through the Use of a Quick-Assessment Tool. Journal of the Canadian Health Libraries Association, 35(3),116-123. doi: 10.5596/c14-030
Elizabeth Margaret Stovold
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Vaasan keskussairaalan psykiatrian yksikön potilaskirjaston toiminnan kehittäminen [PDF]

, 2011
Tutkimuksen tavoitteena oli saada selville, miten ja miksi Vaasan keskussairaalan psykiatrian yksikön potilaskirjastoa haluttaisiin kehittää ja millaiset mahdollisuudet siihen on.
Vuoto, Jonna
core  

Great Library Events: From Planning to Promoting to Evaluation

Journal of the Medical Library Association, 2022
Anne Romano
doaj   +1 more source

Non-pharmacological interventions to support coronary artery bypass graft (CABG) patient recovery following discharge: protocol for a scoping review

BMJ Open
Background In Canada, approximately 15 000 people undergo coronary artery bypass grafting (CABG) each year. However, 9.5% of these patients are urgently readmitted to hospital within 30 days of surgery.
Janet A Curran, Robert Wells, Gillian Sheppard, Alison Farrell, Justin Nathan Billard   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source