Results 101 to 110 of about 760,216 (304)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Exploring family participation in patient care on acute care wards: A mixed‐methods study

, 2020
BACKGROUND: Patient- and family-centred care practices are a recommended part of contemporary care for the acutely ill hospitalized adult patients.
Marion L. Mitchell, Benjamin R. Mackie, Mitchell, Marion L, Andrea P. Marshall, Marshall, Andrea P, Mackie, Benjamin R   +5 more
core   +1 more source

Elderly patients' participation in clinical trials

Perspectives in Clinical Research, 2015
The elderly population is a large and the fastest-growing portion of the population worldwide. The elderly make up the lion's share of patients for certain health conditions including cancer, cardiovascular disease, arthritis, and Parkinson's disease, among others in most parts of the world.
Premnath Shenoy, Anand Harugeri
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study of Nurses\' Willingness to Patient Participation in Patient Safety in Hospitals Affiliated to Tehran University of Medical Sciences Using PaCT-HCW Questionnaire

پیاورد سلامت, 2019
Background and Aim: Patient participation is a widespread concept and is considered as an important issue for improving the quality of patient care and patient safety, which has been considered by health managers.
Maryam Amini, Leila Nazarimanesh, Mahmoud Mahmoudi Majdabadi Farahani   +2 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Patient participation during and after a self-management programme in primary healthcare – The experience of patients with chronic obstructive pulmonary disease or chronic heart failure

, 2018
OBJECTIVE: Patient participation is facilitated by patients' ability to take responsibility for and engage in health issues. Yet, there is limited research as to the promotion of these aspects of patient participation in long-term healthcare interactions.
Marie Holmefur, Kristina Luhr, Kersti Theander, Luhr, Kristina,, Holmefur, Marie,, Eldh, Ann Catrine,, Ann Catrine Eldh, Theander, Kersti,   +7 more
core   +1 more source

Homeless and marginally housed Veteran perspectives on participating in a photo-elicitation research study

Patient Experience Journal, 2018
Photo-elicitation interviewing (PEI) seems a valuable tool for engaging marginalized populations in research despite documented challenges. Given limited data on acceptability of PEI among homeless and marginally housed Veterans, this evaluation aimed to
Keri Rodriguez, Daniel Hedayati, Lauren Broyles, Melissa Wieland, Michael Mitchell, James Conley, Shaddy Saba, Adam Gordon   +7 more
doaj  

Treatment confidence and patient participation in multidisciplinary tumor conferences: A structural equation modeling approach

Cancer Medicine
Objective Multidisciplinary tumor conference (MTC) is a key instrument in multidisciplinary cancer care. In recent years, if and how patient participation in MTC can contribute to a more patient‐centered care have been scientifically discussed.
Marie Degenhardt, Nicole Ernstmann, Barbara Schellenberger, Lena Ansmann, Christian Heuser   +4 more
doaj   +1 more source

Instruments for Patient Education: Psychometric Evaluation of the Expected Knowledge (EKhp) and the Received Knowledge of Hospital Patients (RKhp)

Journal of Multidisciplinary Healthcare, 2020
Helena Leino-Kilpi,1,2 Saija Inkeroinen,1 Esther Cabrera,3,4 Andreas Charalambous,1,5 Natalja Fatkulina,6,7 Jouko Katajisto,8 Árún K Sigurðardóttir,9,10 Panayota Sourtzi,11 Riitta Suhonen,1,2,12 Adelaida Zabalegui,13,14 Kirsi ...
Leino-Kilpi H, Inkeroinen S, Cabrera E, Charalambous A, Fatkulina N, Katajisto J, Sigurðardóttir ÁK, Sourtzi P, Suhonen R, Zabalegui A, Valkeapää K   +10 more
doaj