Results 81 to 90 of about 363,979 (334)

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Patient Positioning [PDF]

open access: yesAORN Journal, 1987
B J, Gruendemann, M H, Meeker
openaire   +2 more sources

Hepatocellular Carcinoma in HIV-Positive Patients

open access: yes, 2013
Highly active antiretroviral therapy (HAART) has dramatically changed the natural history of HIV-1-infected patients leading to increased survival and a better quality of life. Hepatitis C virus (HCV) and hepatitis B virus (HBV) infections are common among HIV-1-infected subjects and represent the most important risk factors for hepatocellular ...
Nunnari G   +10 more
openaire   +6 more sources

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Multi-Criteria Optimization for Image Guidance [PDF]

open access: yesarXiv, 2011
Purpose: To develop a multi-criteria optimization framework for image guided radiotherapy. Methods: An algorithm is proposed for a multi-criteria framework for the purpose of patient setup verification decision processes. Optimal patient setup shifts and rotations are not always straightforward, particularly for deformable or moving targets of the ...
arxiv  

Hysterectomy with the patient's position

open access: yesJournal of obstetrics and women's diseases, 2012
The authors analyzed patient awareness about the forthcoming operation in the amount of hysterectomy in aspect of the information obtained about the nature of disease, especially surgical approach, potential complications and long-term results of treatment.
Elena O Sazonova   +3 more
openaire   +2 more sources

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Clinical Validation of two Surface Imaging Systems for Patient Positioning in Percutaneous Radiotherapy [PDF]

open access: yesarXiv, 2016
Precise patient positioning and thus precise positioning of the planning target volume (PTV) is a prerequisite for effective treatment in percutaneous radiation therapy. Conventional imaging modalities used to ensure exact positioning for treatment typically involve additional radiation exposure of the patient. A different approach to patient alignment
arxiv  

Using Deep Learning and Explainable Artificial Intelligence in Patients' Choices of Hospital Levels [PDF]

open access: yesarXiv, 2020
In countries that enabled patients to choose their own providers, a common problem is that the patients did not make rational decisions, and hence, fail to use healthcare resources efficiently. This might cause problems such as overwhelming tertiary facilities with mild condition patients, thus limiting their capacity of treating acute and critical ...
arxiv  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

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