Results 61 to 70 of about 745,959 (309)

Patients' perspectives and preferences in the choice of inhalers: the case for Respimat® or HandiHaler® [PDF]

, 2016
Poor inhaler technique hampers the efficacy of drug therapy in asthma and chronic obstructive pulmonary disease. Not only does this affect individual patient care, but it also impacts on the wider health care economics associated with these conditions ...
Dekhuijzen, PNR, Lavorini, F, Usmani, OS
core   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Shared decision-making about cardiovascular disease medication in older people: A qualitative study of patient experiences in general practice [PDF]

, 2019
Objectives To explore older people's perspectives and experiences with shared decision-making (SDM) about medication for cardiovascular disease (CVD) prevention.
Bonner, Carissa, Doust, Jenny, Jansen, Jesse, McCaffery, Kirsten, McKinn, Shannon, Muscat, Danielle Marie   +5 more
core   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

A review of studies mapping (or cross walking) from non-preference based measures of health to generic preference-based measures [PDF]

, 2008
This paper presents a systematic review of current practice in mapping between nonpreference based measures and generic preference-based measures.
Brazier, J.E., Tsuchiya, A., Yang, Y.
core   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Optimal Physicians’ Attire: Patients’ and Physicians’ Preference

Siriraj Medical Journal, 2020
Background: The use of a white coat has been less popular in some countries due to the spread of healthcare-associated infection and changing doctor-patient relationship towards provider-patient relationship. Objective: To identify optimal physiciansâ€
Suwannee Suraseranivongse, Kaittiyos Kuldejchaichan, Arunee Leesirichaiku   +2 more
doaj  

Comparative Study Between Peristomal Patches in Patients with Definitive Tracheostomy

International Archives of Otorhinolaryngology, 2018
Introduction To prevent or diminish pulmonary problems in laryngectomized patients, continuous use of a heat and moisture exchanger (HME) is recommended. Therefore, automatic speaking valves are also often combined with an HME to enable hands-free speech.
Liset Lansaat, Bertram de Kleijn, Frans Hilgers, Bernard van der Laan, Michiel van den Brekel   +4 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Preferences for colorectal cancer screening tests and screening test use in a large multispecialty primary care practice [PDF]

, 2012
BACKGROUND: The purpose of this study was to identify factors associated with colorectal cancer (CRC) screening test preference and examine the association between test preference and test completed. METHODS: Patients (n = 1224) were 50‐70 years, at
Almog, DeBourcy, Degner, Hawley, Hosmer, Janz, Klabunde, Klabunde, Lafata, Lantz, Leard, Ling, Ling, McQueen, McQueen, Meissner, Partin, Pignone, Powell, Ruffin, Schroy, Schroy, Smith, Steinwachs, U.S. Preventive Services Task Force. Screening for colorectal cancer: U.S., Vernon, Vernon, Vernon, Wolf   +28 more
core   +1 more source