Results 81 to 90 of about 1,321,475 (298)

Incorporating development of a patient-reported outcome instrument in a clinical drug development program: examples from a heart failure program. [PDF]

, 2016
BackgroundPatient-reported outcome (PRO) measures can be used to support label claims if they adhere to US Food & Drug Administration guidance. The process of developing a new PRO measure is expensive and time-consuming.
Anatchkova, Milena, Chau, Dina, Malik, Fady I, Oko-Osi, Hafiz, Patrick, Donald L, Spertus, John, Teerlink, John R, von Maltzahn, Robyn, Wiklund, Ingela   +8 more
core   +1 more source

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Patient-Reported Outcomes in Integrated Care: A Frontier of Opportunities and Challenges

International Journal of Integrated Care
Effective care integration requires the right information, at the right time, with care and support delivered in the right environment. Patient-reported outcome measures [PROMs] offer a mechanism to support collaborative integrated care to help people ...
Nicola Anderson, Sarah E. Hughes, Olalekan L. Aiyegbusi, Philip Collis, Robin Miller, Melanie Calvert   +5 more
doaj   +1 more source

Reliability and validity of an Ambulance Patient Reported Experience Measure (A-PREM): pilot study [PDF]

, 2017
Background There are no prehospital ambulance Patient Reported Experience Measures (A-PREMs) routinely used to support service comparisons and improvement.
Akanuwe, Joseph, Siriwardena, Niro, Spaight, A., Togher, Fiona   +3 more
core   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Shared-decision-making, trust in the healthcare system and health literacy are associated with self-reported pain levels: a population-based cross-sectional study in individuals living with a chronic health condition in Wales

BMC Health Services Research
Background Pain is an invisible condition which has significant morbidity, mortality and healthcare system burden, and is a leading cause of disability worldwide.
Katherine E. Woolley, Nichola Thuvesholmen, Sarah Puntoni, Sally Cox, Alexander Shaw, Owen Hughes, Kathleen Withers   +6 more
doaj   +1 more source

Patient Reported Experience Measures (PREM) in onkologischen Schwerpunktpraxen

, 2018
Hintergrund: Bei Patientenbefragungen zur Zufriedenheit mit der Versorgung in Praxen oder Krankenhäusern können Deckeneffekte entstehen, d.h. es werden leicht die besten Werte erreicht. Im Rahmen der Qualitätssicherung verringert sich dadurch der Informationsgehalt der Ergebnisse, es [zum vollständigen Text gelangen Sie über die oben angegebene URL]
Hermes-Moll, K, Baumann, W, Heidt, V
openaire   +1 more source

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata, Keita Ueda, Tsukasa Ueno, Katsutsugu Umeda, Kentaro Ueno, Kanade Tanaka, Noyuri Nishida, Rie Yamawaki, Megumi Nukui, Yoshiki Arakawa   +9 more
wiley   +1 more source

Patient Reported Experience Measures in navigated Transcranial Magnetic Stimulation [PDF]

Neuro-Oncology, 2019
Abstract Introduction Navigated Transcranial Magnetic Stimulation (nTMS) is a non-invasive adjunct used in surgical planning for lesions in eloquent brain. However, its patient tolerability and effect on their overall healthcare experience is still unknown.
Sabina Patel, José Lavrador, Prajwal Ghimire, Richard Gullan, Keyoumars Ashkan, Ranjeev Bhangoo, Francesco Vergani   +6 more
openaire   +1 more source

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane, Wei Xue, Amira Qumseya, Thomas Scharschmidt, Kathryn R. Tringale, Oscar Lopez Nunez, Jiaqi Hu, Donald A. Barkauskas, Rajkumar Venkatramani, Sheri L. Spunt, Aaron R. Weiss, Noah C. Federman   +11 more
wiley   +1 more source