Results 191 to 200 of about 1,811,722 (264)

Patient-Reported-Outcome-Measures (PROMs) After Gastrointestinal Endoscopic Resections. [PDF]

United European Gastroenterol J
Retzbach L, Fuchs KH, Brand M, Lux TJ, Meining A.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Patient-reported Outcome Measures in Pediatric Orthopaedics. [PDF]

J Pediatr Soc North Am
Mohr M, McClure PK, Nowlan NC, Green CJ.
europepmc   +1 more source

Patient-Reported Outcomes, Patient-Reported Information

The Patient: Patient-Centered Outcomes Research
Baldwin, Mike, Spong, Andrew, Doward, Lynda, Gnanasakthy, Ari   +3 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Patient-reported outcome measures in prostate research: a scoping review. [PDF]

BJU Int
Young GJ, Walsh EI, Lane JA, Donovan JL, Drake MJ, Pedder H, Metcalfe C.   +6 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Physiotherapist and nurse perspectives on the acceptability and timing of patient-reported outcome measures in clinical practice: Balancing standardisation and flexibility. [PDF]

Qual Life Res
Nikolovski J, Franklin M, Morton RL, Armstrong M, Hartas G, Rossiter B, Fagan M, Tinsley M, Levesque JF, Sutherland K, Mercieca-Bebber R, Snyder C, Aiyegbusi OL, Power R, De Lisser-Howarth T, Troiani JP, Maher J, Leonard J, Elias K, Rutherford C.   +19 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Erratum to 'Longitudinal evaluation of patient-reported outcome measures and clinician-based scores after reverse shoulder arthroplasty in Asian patients: patient-reported outcome measures may be sufficient beyond 1 year' [JSES International Volume 10 Issue 3 (2026) 101,646]. [PDF]

JSES Int
Hirakawa Y, Manaka T, Nakazawa K, Ito Y, Ogura A, Takahashi Y, Hasegawa Y, Igawa A, Terai H.   +8 more
europepmc   +1 more source