Results 211 to 220 of about 7,534,100 (256)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Patient‐reported outcomes and patient voices

Seminars in Dialysis, 2022
AbstractOnline hemodiafilration (HDF) treatment may be associated with better quality of life due to improved clearance of middle‐molecular‐weight uremic toxins and hemodynamic stability in dialysis patients, in addition to better overall survival.
Asci, Gulay, Ok, Ercan
openaire   +3 more sources

Patient-Reported Outcomes in Patients with Cardiomyopathy

Current Cardiology Reports, 2021
As medicine strives to become more patient-centered, patient-reported outcomes (PROs) are often used to describe patients' symptoms, function, and quality of life. This review describes the key concepts of PROs specific to heart failure in clinical trials and their potential role in clinical practice.As the Food and Drug Administration has increasingly
Raul Angel Garcia   +2 more
openaire   +2 more sources

Patient-reported outcomes in vasculitis

Best Practice & Research Clinical Rheumatology, 2023
Systemic vasculitis encompasses a group of multisystem disorders; both the diseases and the treatment strategies can have a significant impact on a patient's health-related quality of life (HRQoL). Using patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) to evaluate the patient's view of their condition ...
Helena Crawshaw   +5 more
openaire   +2 more sources

Patient-reported Outcomes in Arthrogryposis

Journal of Pediatric Orthopaedics, 2020
Background: Little is known about patient-reported health status in children and adolescents with arthrogryposis. Utilizing the Patient-Reported Outcome Measurement Information System (PROMIS) and Pediatric Outcomes Data Collection Instrument (PODCI) questionnaires, we investigated functional and psychosocial measures in ...
Lindley B, Wall   +4 more
openaire   +2 more sources

Patient-Reported Outcomes in Lupus

Rheumatic Disease Clinics of North America, 2021
Patient-reported outcome (PRO) was identified as a core systemic lupus erythematosus (SLE) outcome in 1999. More than 20 years later, however, generic PRO measures evaluating impact in SLE are used mainly for research. Generic and disease-targeted PRO tools have unique advantages.
Narender, Annapureddy, Meenakshi, Jolly
openaire   +2 more sources

Patient Reported Outcomes

B&G Bewegungstherapie und Gesundheitssport, 2020
ZusammenfassungBewegungs- und sporttherapeutische Maßnahmen bilden einen festen Therapiebestandteil im Rahmen der multidisziplinären Rehabilitation von alkoholabhängigen Menschen. Dies begründet sich aus den suchtbedingten Folgen im physischen, psychischen und sozialen Bereich.
Hubertus Deimel, Chloé Chermette
openaire   +2 more sources

‘The patient’: at the center of patient-reported outcomes

Expert Review of Pharmacoeconomics & Outcomes Research, 2015
The recent emphasis of including patient reports in their own care management is reviewed in terms of the factors that contributed to its popularity. The role change of patients as being active participants in their own care as a result of the rising consumerism and advocacy has led to increased pressures for including patients in the therapeutic ...
openaire   +2 more sources

Patient-Reported Outcomes in Myositis

Rheumatic Disease Clinics of North America
Idiopathic inflammatory myopathies (IIM) impact patients' lives in diverse and complex ways beyond their muscle weakness. Patient-reported outcomes (PROs), which directly measure patients' daily experience with IIM without interpretation of care providers, are crucial to assess the real-world impact of IIM.
Jin Kyun, Park, Christopher A, Mecoli
openaire   +2 more sources

Interpretation of patient-reported outcomes

Statistical Methods in Medical Research, 2013
A patient-reported outcome is any report on the status of a patient’s health condition that comes directly from the patient. Clear and meaningful interpretation of patient-reported outcome scores are fundamental to their use as they can be valuable in designing studies, evaluating interventions, educating consumers, and informing health policy makers ...
Joseph C, Cappelleri   +1 more
openaire   +2 more sources

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