Results 161 to 170 of about 1,479,071 (353)

Editor's Spotlight/Take 5: Readability of Orthopaedic Patient-reported Outcome Measures: Is There a Fundamental Failure to Communicate? [PDF]

, 2017
Daniel M. Wongworawat
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Barriers and enablers to the implementation of patient-reported outcome and experience measures (PROMs/PREMs): protocol for an umbrella review

Systematic Reviews
Background Patient-reported outcome and experience measures (PROMs and PREMs, respectively) are evidence-based, standardized questionnaires that can be used to capture patients’ perspectives of their health and health care.
Guillaume Fontaine, Marie-Eve Poitras, Maxime Sasseville, Marie-Pascale Pomey, Jérôme Ouellet, Lydia Ould Brahim, Sydney Wasserman, Frédéric Bergeron, Sylvie D. Lambert   +8 more
doaj   +1 more source

Patient-Reported Outcome Measures in Safety Event Reporting: PROSPER Consortium Guidance [PDF]

, 2013

core   +1 more source

Validation studies of rheumatoid arthritis patient-reported outcome measures in populations at risk for inequity: A systematic review and analysis using the OMERACT summary of measurement properties equity table

, 2022
Cheryl Barnabé, Aimée Wattiaux, Jennifer Petkovic, Dorcas Beaton, Beverley Shea, Regina Greer-Smith, Jennifer Humphreys, Christie M. Bartels, Peter Tugwell, Valerie Umaefulam   +9 more
openalex   +1 more source

Reporting of Patient‐Reported Outcome Measures in Randomized Controlled Trials on Shoulder Rotator Cuff Injuries Is Suboptimal and Requires Standardization [PDF]

, 2022
Lydia Brock, Brooke Hightower, Ty Moore, Danya Nees, Benjamin Heigle, Samuel Shepard, Micah Kee, Ryan Ottwell, Micah Hartwell, Matt Vassar   +9 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Patient-reported outcome measures and patient-reported experience measures [PDF]

BJA Education, 2017
Charlotte Kingsley, Sanjiv Patel
openaire   +1 more source

The challenges and opportunities of using patient reported outcome measures (PROMs) in clinical practice

, 2018
Michael Fleischmann, Brett Vaughan
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source