Results 181 to 190 of about 1,479,071 (353)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Studying the impact of a medication use evaluation by the community pharmacist (Simenon): Patient-reported outcome measures

, 2020
Joke Wuyts, Joris Maesschalck, Isabelle De Wulf, Jan De Lepeleire, Veerle Foulon   +4 more
openalex   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Patients Reported Outcomes Measures (PROMs) Trajectories After Elective Hip Arthroplasty: A Latent Class Growth Analysis [PDF]

, 2021
Davide Golinelli, Alberto Grassi, Dario Tedesco, Francesco Sanmarchi, Simona Rosa, Paola Rucci, Marilina Amabile, Monica Cosentino, Barbara Bordini, Maria Pia Fantini, Stefano Zaffagnini   +10 more
openalex   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Psychometric properties of patient-reported outcome measures for periacetabular osteotomy [PDF]

, 2019
Clohisy, John C, Pascual-Garrido, Cecilia, Wasko, Marcin K, Yanik, Elizabeth L   +3 more
core   +1 more source

Additional file 2 of Unlocking patient insights: a prospective study on patient reported outcome measures in thoracic surgery

Marco Nicolas Andreas, Carlo Jurth, Jan C. Schmid, L. S. Weber, Falk von Dincklage, Aina Lask, J Strauchmann, Johann Pratschke, Jens C. Rückert, Jens Neudecker, Tomasz Dziodzio   +10 more
openalex   +1 more source

Additional file 4: of A review of patient-reported outcome measures to assess female infertility-related quality of life

, 2017
Helen Kitchen, Natalie V. J. Aldhouse, Andrew Trigg, R. Palencia, Stephen Mitchell   +4 more
openalex   +1 more source

Patient-reported outcome measures in cardiac surgery: A systematic review. [PDF]

JTCVS Open
Rosgen BK, Bele S, Ahmed S, Kemp K, Santana MJ, Gregory AJ.   +5 more
europepmc   +1 more source