Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
Validation of the Patient-Reported Outcome Measures Tool "Catquest" in Odia Language. [PDF]
CureusSen S, Das M, Ak K, Mohanty A, Goel A.
europepmc +1 more source
Feasibility of 4 patient-reported outcome measures in a registry setting
, 2012 Aksel Paulsen +3 more
openalex +2 more sources
What Is the Value of the Routine Use of Patient-Reported Outcome Measures Toward Improvement of Patient Outcomes, Processes of Care, and Health Service Outcomes in Cancer Care? A Systematic Review of Controlled Trials [PDF]
, 2014 Grigorios Kotronoulas +6 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Patient-Reported Outcome Measures in CKD-Associated Pruritus: A Systematic Review. [PDF]
Kidney MedBai L, Shi J, Du X.
europepmc +1 more source
Can the outcome of primary care be measured by a Patient Reported Outcome Measure? [PDF]
, 2014 Mairead Murphy +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Sample size used to validate a scale: a review of publications on newly-developed patient reported outcomes measures [PDF]
, 2014 Emmanuelle Anthoine +4 more
openalex +1 more source