Results 131 to 140 of about 561,797 (309)

Crying baby gets the milk? The governmentality of grievance redressal for patient rights violations in Karnataka, India. [PDF]

BMJ Glob Health, 2022
Putturaj M, Krumeich A, Nuggehalli Srinivas P, Engel N, Criel B, Van Belle S.   +5 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Ocena stopnia poinformowania oraz wiedzy pacjentów na temat badania elektroencefalograficznego = Evaluation level of information and knowledge of patients about the study electroencephalographic

Journal of Education, Health and Sport, 2015
Zych Justyna, Skonieczna Joanna, Olejniczak Dominik, Zakrzewska Karolina. Ocena stopnia poinformowania oraz wiedzy pacjentów na temat badania elektroencefalograficznego = Evaluation level of information and knowledge of patients about the study ...
Justyna Zych, Joanna Skonieczna, Dominik Olejniczak, Karolina Zakrzewska   +3 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Patients' rights in Kashmir [PDF]

The Lancet, 2020
Muhammad Magdi, Yaqoob, Kieran, McCafferty   +1 more
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

RIGHTS AND RESOURCES [PDF]

, 2002
Acknowledgements -- Series preface -- Introduction -- Pt. I. The rights-resources relationship -- Ch. 1. 'Shifting paradigms in bioethics and health law: the rise of a new pragmatism', American Journal of Law and Medicine, 20 / Susan M. Wolf (1994) --
Miller, Frances H.
core  

Artificial or Human Intelligence: Who is to Blame?

Journal of the Belgian Society of Radiology, 2018
Nils Broeckx, Christophe Lemmens
doaj   +1 more source

Oncologists' reflections on patient rights and access to compassionate use drugs: A qualitative interview study from an academic cancer center. [PDF]

PLoS One, 2021
Stout J, Smith C, Buckner J, Adjei AA, Wentworth M, Tilburt JC, Master Z.   +6 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source