Results 61 to 70 of about 1,366,479 (307)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Truth-telling to the patient, family, and the sexual partner: a rights approach to the role of healthcare providers in adult HIV disclosure in China. [PDF]

open access: yes, 2014
Patients' rights are central in today's legislation and social policies related to health care, including HIV care, in not only Western countries but around the world.
Beachamp T. L.   +22 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Clerics\' Perception of Patient Rights: A Qualitative Content Analysis

open access: yesHealth, Spirituality and Medical Ethics, 2022
Background and Objectives: Patients have certain rights that are expected to be observed and respected by healthcare providers. These rights include universal as well as local rights determined by the social and cultural context of any society. Patient’s
Akram Heidari   +3 more
doaj  

Solidarity and Social Justice in Promoting Mental Health and Wellness among Impoverished People: Looking from Mercy and Liberation [PDF]

open access: yes, 2018
This paper reflects on issues of justice and mental health from a theological approach that intends to show an ethics of social responsibility and caring ground on a new social Samaritan paradigm.
Martins, Alexandre Andrade
core   +1 more source

Clinical proteomics for precision medicine: the bladder cancer case [PDF]

open access: yes, 2017
Precision medicine can improve patient management by guiding therapeutic decision based on molecular characteristics. The concept has been extensively addressed through the application of –omics based approaches.
Frantzi, Maria   +4 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Review on Some Aspects of Patient’ Rights in Clinical Education [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2012
Clinical education will be possible with involving patients. Many patients who seek medical and diagnostic care can be involved in clinical training. Therefore, teachers and students need to know the legal aspects of patient involvement and adhere to ...
Athar Omid   +5 more
doaj  

Evaluation of a Multidisciplinary Extracurricular Event Using Kolb’s Experiential Learning Theory: A Qualitative Study [Letter]

open access: yesJournal of Multidisciplinary Healthcare, 2023
Hasta Handayani Idrus,1,* Mustamin Mustamin,2,* Zulfahmidah3,* 1Department of Microbiology, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia; 2Department of Nutrition, Polytecnic Ministry of Health, Makassar, Indonesia ...
Idrus HH, Mustamin M, Zulfahmidah
doaj  

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