Results 91 to 100 of about 2,463,575 (352)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Increase Noted in Reported Wrong-Site Surgery Events From Interventional Radiology
Patient Safety, 2023 Patient Safety Authority
doaj +1 more source
Patient Safety, 2019 Falls are a common and often devastating health threat for hospitalized patients, as they can cause serious injuries such as a hip fracture, and even lead to death.1 Falls in Pennsylvania continue to be one of the biggest contributors to patient harm and
Susan C. Wallace, Caitlyn Allen
doaj +1 more source
Advancing Patient Safety in the U.S. Department of Veterans Affairs [PDF]
, 2011 As part of a systemwide transformation, the VA formed its National Center for Patient Safety to foster an organizational culture of safety within its nationwide network of hospitals and outpatient clinics.
Deborah Chase, Douglas McCarthy
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Patient Safety, 2019 A battery's moment of death may come as a beep, a red warning light, or a complete surprise. If you are lucky (i.e., prepared), you have a power cord or backup battery handy.
Kim Liberatore, Barry Kohler
doaj +1 more source
Adverse events in veterans affairs inpatient psychiatric units: Staff perspectives on contributing and protective factors. [PDF]
, 2017 OBJECTIVES: This study sought to identify risk factors and protective factors in hospital-based mental health settings in the Veterans Health Administration (VHA), with the goal of informing interventions to improve care of persons with serious mental ...
Cullen, Sara W. +4 more
core +1 more source