Results 111 to 120 of about 2,641,102 (341)

Patient selection and outcomes of liver transplantation for adult patients with Wilson disease: a single center experience

, 2022
Shin Hwang, Minjae Kim, Minjae Kim, Chul-Soo Ahn, Deok‐Bog Moon, Tae‐Yong Ha, Gi‐Won Song, Dong‐Hwan Jung, Gil‐Chun Park, Woo‐Hyoung Kang   +9 more
openalex   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Improving Patient Selection and Prioritization for Hospital at Home Through Predictive Modeling. [PDF]

, 2022
Satyabrata Pati, Gina E Thompson, Christopher J Mull, Daniel H Allen, Jacey R. Fazio, Heidi Felix, Margaret R. Paulson, Rajeev Chaudhry, Gautam Matcha, Michael J. Maniaci, Charles D. Burger, Daniel Quest   +11 more
openalex  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

A pilot study on record reviewing with a priori patient selection [PDF]

, 2013
Sezgin Cihangir, Ine Borghans, Karin Hekkert, H. P. Muller, Gert P. Westert, Rudolf B Kool   +5 more
openalex   +1 more source

Minimally invasive pelvic exenteration for gynaecological malignancies: the challenge of patients’ selection [PDF]

, 2023
Nicolò Bizzarri, Vito Chiàntera, Matteo Loverro, Alfredo Ercoli, Giuseppe Vizzielli, Giovanni Scambia   +5 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Minimizando perdas e maximizando eficiência na detecção de casos de desnutrição aguda severa

Revista de Saúde Pública
OBJETIVO: Alguns dos muitos desafios enfrentados por epidemiologistas são planejar adequadamente e otimizar o processo de captação de sujeitos em termos de efetividade e eficiência.
Michael E Reichenheim, Maria Helena Hasselmann   +1 more
doaj  

Inferring Hospital Quality from Patient Discharge Records Using a Bayesian Selection Model [PDF]

This paper develops new econometric methods to estimate hospital quality and other models with discrete dependent variables and non-random selection. Mortality rates in patient discharge records are widely used to infer hospital quality.
Gautam Gowrisankaran, Robert J. Town
core  

Tofacitinib in the management of active psoriatic arthritis: patient selection and perspectives. [PDF]

, 2019
Tofacitinib is an oral Janus kinase inhibitor approved for the treatment of psoriatic arthritis (PsA). It provides an alternative option for patients who have had an inadequate response and tolerance to other disease modifying antirheumatic drugs (DMARDs)
Beck, Kristen M, Liao, Wilson, Ly, Karen, Orbai, Ana-Maria, Smith, Mary P   +4 more
core