Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Subtotal cholecystectomy as a bailout strategy in difficult cholecystectomy: Outcomes and patient selection criteria. [PDF]
Öcal İH, Hatipoğlu S.
europepmc +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Prognostic Models for Patient Selection in Palliative Bone Radiotherapy: A Systematic Review. [PDF]
Martins FA, Brito N, Sousa D.
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Optimizing the "right" patient selection for treatment for sickle cell disease. [PDF]
Colombatti R, Reggiani G.
europepmc +1 more source
Correction to: "Diazoxide Choline Extended-Release (DCCR) Use in Prader-Willi Syndrome: Patient Selection, Dosing, and Management". [PDF]
europepmc +1 more source
Lumbar Sympathetic Radiofrequency Ablation for Peripheral Arterial Disease: Considerations Regarding Patient Selection and Interpretation of Short-Term Outcomes [Letter]. [PDF]
Çelik G.
europepmc +1 more source
Artificial intelligence for patient selection in pulsed-field ablation: promise, pragmatism, and the need for standards. [PDF]
Rohrer U, Duncker D.
europepmc +1 more source
Vestibular schwannoma microsurgery in the era of multimodal treatment: advances in technique and patient selection. [PDF]
Albalkhi I +4 more
europepmc +1 more source

