Results 41 to 50 of about 24,626 (268)
JPP (Jurnal Politik Profetik)This study examines the role and impact of political patronage on Indonesia’s governance and its contribution to the power disparity. It offers strategies to mitigate patronage’s negative effects and promote effective governance, highlighting its ...
Rahmat Kurniawan
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Journal of Associated Medical Sciences, 2008 Background: One of the major problems in blind children is low efficiency in Brailles’ writing and reading skills. Intervention program that can be used to enhance these abilities was sensory stimulation.
Supaporn Chinchai +3 more
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Perceptions of service quality dimensions and patronage of street food vendors in South African townships [PDF]
The Retail and Marketing Review, 2020 Street food vendors are common in South Africa’s townships and are typically patronised by individuals in lower- income brackets. The extent to which service quality considerations play a role in the patronage of such informal, survivalist ...
Prof CE Eresia-Eke +2 more
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Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Musicology Today, 2020 As a result of the Glorious Revolution of 1688, James II Stuart lost the throne of England, Scotland, and Ireland. He spent the last years of his life in France, in residence offered to his family and court by Louis XIV.
Markuszewska Aneta
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
La Florida del Inca. Garcilaso in His Many Names
Iberoamericana. América Latina - España - Portugal, 2019 This article explores the treatment the Inca gives to the many names of his relatives, protectors and potential patrons in four paratexts to La Florida: Relación de la descendencia..., his hitherto unknown Epítome del descubrimiento..., the dedicacy to ...
José Miguel Martínez Torrejón
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