Results 51 to 60 of about 48,705 (289)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Addressing emotional aggression in Thai adolescents: evaluating the P-positive program using EQ metric

open access: yesInternational Journal of Adolescent Medicine and Health
This study investigates the effectiveness of the P-Positive program in addressing emotional aggression among junior high school students in Lopburi Province, Thailand.
Junsomang Sujinun   +8 more
doaj   +1 more source

Effect of Board Games on the Social Skills Development of At-Risk Children with Attention Deficit Hyperactivity Disorder (ADHD) in Upper Elementary Schools in Thailand

open access: yesJournal of Health Science and Medical Research (JHSMR)
Objective: This study investigated the impact of board games on social skills development among at-risk children diagnosed with attention deficit hyperactivity disorder (ADHD) in upper elementary schools in Thailand.
Rattanaporn Arsa   +7 more
doaj   +1 more source

Diakonos and prostatis: Women’s patronage in Early Christianity

open access: yesHTS Teologiese Studies/Theological Studies, 2005
In spite of numerous studies on the patronage system in Mediterranean antiquity, little attention has been paid to either how the patronage of women was part of the system or how it differed. In fact, there is substantial evidence for women’s exercise of
Carolyn Osiek
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Patronage Appointments in Brazil, 2011–2019

open access: yes, 2022
Brazil is widely regarded in the comparative politics literature as a country in which the tensions between bureaucrats and politicians illustrate the dilemmas of building coalitions, managing state-owned enterprises, and providing basic public services (
Fernanda Odilla   +2 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Building customer patronage in app-based sharing economy firms: insights from Indian consumers

open access: yesCogent Business & Management
This study adapts retail patronage theory to app-based sharing economy (SE) platforms. It develops a framework explaining customer patronage behavior in digitally mediated service contexts. While prior research has examined individual drivers of platform
Shivan Sanjay Patel   +3 more
doaj   +1 more source

¿Reserva pontificia o atributo soberano? La concepción del patronato en disputa. Chile y la Santa Sede (1810-1841)

open access: yesHistoria Crítica, 2014
This paper focuses on the various concepts of patronage that were held in Chile after the formation of the ¡unta Gubernativa of 1810 and the relation with the Holy See in the context of the exercise of republican patronage.
Lucrecia Raquel Enríquez
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

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