Results 41 to 50 of about 69,114 (280)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Academic Patronage

open access: yes, 2009
Patronage, expansively conceived as covering all forms of bias and discrimination, is pervasive in organisations and professions, including academia. Four key types of academic patronage operate through decisions made, processes used, assistance given to
Martin, Brian, Brian Martin
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A PLS-SEM decision model of repeat patronage among generation Z: Retail environment quality, experiential strategy, and memorable experience [PDF]

open access: yesDecision Science Letters
This study develops a decision-oriented model of repeat patronage among Generation Z visitors to shopping malls in Bali by examining how two controllable managerial inputs, retail environment quality and experiential retail strategy, influence
Ida Bagus Raka Suardana   +5 more
doaj   +1 more source

Perceived service recovery justice and customer re-patronage intentions: Sequential mediation

open access: yesCogent Business & Management, 2021
The aims of this time-lagged study are twofold, first to identify the effect of perceived justice (as a second-order construct) on recovery satisfaction and customer affection; secondly, to investigate the effect of customer affection and recovery ...
Muhammad Asghar Ali   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artistic patronage in late medieval Troyes, 1380-1520 [PDF]

open access: yes, 2013
This thesis explores the development of artistic patronage in the city of Troyes between 1380 and 1520. It takes into consideration the patrons and artists involved in the creation of manuscript illumination, sculpture, metalwork, panel painting ...
Wyant, Cody James
core   +2 more sources

Las discusiones sobre el patronato en Colombia en el siglo XIX

open access: yesHistoria Crítica, 2014
This paper aims to show that, despite it being a relevant topic, patronage has not been sufficiently studied by Colombian historians. With this objective in mind, it studies the discussions generated by the republican patronage in Colombia in the 19th ...
José David Cortés Guerrero
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Addressing emotional aggression in Thai adolescents: evaluating the P-positive program using EQ metric

open access: yesInternational Journal of Adolescent Medicine and Health
This study investigates the effectiveness of the P-Positive program in addressing emotional aggression among junior high school students in Lopburi Province, Thailand.
Junsomang Sujinun   +8 more
doaj   +1 more source

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