Results 41 to 50 of about 48,705 (289)

How consumers’ need for variety and social consumption influences festival patronage and spending [PDF]

open access: yes, 2022
This paper investigates the influence of motivational goals such as variety seeking and social consumption on consumers’ patronage and spending at craft beer festivals.
Cui, C.   +3 more
core   +1 more source

Las discusiones sobre el patronato en Colombia en el siglo XIX

open access: yesHistoria Crítica, 2014
This paper aims to show that, despite it being a relevant topic, patronage has not been sufficiently studied by Colombian historians. With this objective in mind, it studies the discussions generated by the republican patronage in Colombia in the 19th ...
José David Cortés Guerrero
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Reassessing Early Theatre Patronage with New Perspectives on John Dudley

open access: yes, 2022
As studies of early modern English playing companies become increasingly concerned with the active role of the players in promoting the economic, familial, and political interests of their patrons, it also becomes more important that the performance and ...
Johnson, Laurie
core  

‘Pracademics’ as boundary spanners: utilizing AI-powered tools to enhance the inclusive provincial development plan for Sa Kaeo, Thailand

open access: yesFrontiers in Education
IntroductionProvincial development planning in Thailand often faces a disconnect between top-down bureaucratic requirements and bottom-up local needs.
Chaiwut Thepo   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Health Threats among Thai Pilgrims during Pilgrimage to Holy Buddhist Places in India: A Cross-Sectional Descriptive Study

open access: yesJournal of Health Science and Medical Research (JHSMR)
Objective: The pilgrimage to make merit by visiting and paying respect to four sacred Buddhist places in India is a popular tradition among Thai pilgrims. However, health threats are common occurrences during such pilgrimages.
Phannathat Tanthanapanyakorn   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Development and Patronage [PDF]

open access: yes, 1997
Far from being a liberating process for all, much of what has been done in the name of development serves to reinforce the intellectual, material, and financial dependence of those on the receiving end.
Tegegn, Melakou
core  

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