Results 61 to 70 of about 67,249 (274)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Crowd-Patronage – Intermediaries, Geographies and Relationships in Patronage Networks [PDF]
, 2017 This article introduces a new mode of patronage of the arts: crowd-patronage. In so doing the article illustrates the plural roles of intermediaries in patronage networks which go beyond Bourdieuian cultural intermediaries to include regulatory and ...
Swords, Jon, Jon Swords
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Journal of Associated Medical Sciences, 2008 Background: One of the major problems in blind children is low efficiency in Brailles’ writing and reading skills. Intervention program that can be used to enhance these abilities was sensory stimulation.
Supaporn Chinchai +3 more
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JPP (Jurnal Politik Profetik)This study examines the role and impact of political patronage on Indonesia’s governance and its contribution to the power disparity. It offers strategies to mitigate patronage’s negative effects and promote effective governance, highlighting its ...
Rahmat Kurniawan
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Bulletin de l'Union des sociétés de patronage de France
, 1895 Variante(s) de titre : Union des sociétés de patronage de FranceEtat de collection : 1895-1932Avec mode ...
Patronage des libérés. Auteur du texte +2 more
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Elite Patronage and Firm Innovation in China
Journal of Current Chinese AffairsExisting scholarship predominantly examines how elite patronage influences the behaviour of political elites, while the ways in which businesses perceive and respond to patronage dynamics remain understudied. This study addresses this gap by investigating
Yuxing Liang
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Rural patronage in classical Athens
Studia Historica: Historia Antigua, 2011 Recent works have questioned the idea of an absolute replacement of private patronage by a kind of community patronage in Pericles’ times. These reconsiderations have limited the extent of this change, differentiating the urban habitat from the rural one,
Julián GALLEGO
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