Results 191 to 200 of about 74,037 (234)

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source

Solvent‐Guided Chiral Assemblies and Chemical Doping of OEG‐Functionalized Conjugated Polymers

Advanced Materials, EarlyView.
Solvent‐dependent aggregation pathways dictate whether conjugated polymers form chiral lyotropic liquid‐crystalline assemblies or achiral packed aggregates. Mapping solvent‐controlled β₁ and β2 states reveals that weaker backbone association favors β₁ aggregates and reorganizable twisted mesophases, whereas stronger backbone association favors β2 ...
Sanghyun Jeon, Justin Scott Neu, Nahyun Ahn, Ayse Senlik, Yen‐Chi Chen, Pravini S. Fernando, Priyotosh Bairagya, Chetan Kumar Prasad, Janice Mihyun Baek, Wei You, Ying Diao   +10 more
wiley   +1 more source

Overexpression of PSK-γ in Arabidopsis promotes growth without influencing pattern-triggered immunity. [PDF]

Plant Signal Behav, 2019
Liu Y, Zhang D, Li M, Yan J, Luo L, Yu L.   +5 more
europepmc   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

Advanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase, Varsha C. Pujari, Akash V. Fulari, Sunil M. Patange, Sean Li, Danyang Wang, Sagar E. Shirsath   +6 more
wiley   +1 more source

New alleles of Arabidopsis BIK1 reinforce its predominant role in pattern-triggered immunity and caution interpretations of other reported functions

Song B, Choi S, Kong L, Kim S, Fliegmann J, Li X, DeFalco TA, Hu M, Li M, Zhao Y, Wang H, Shan L, Nurnberger T, He P, Zipfel C, Zhou J.   +15 more
europepmc   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

The Lamin-Like LITTLE NUCLEI 1 (LINC1) Regulates Pattern-Triggered Immunity and Jasmonic Acid Signaling. [PDF]

Front Plant Sci, 2019
Jarad M, Mariappan K, Almeida-Trapp M, Mette MF, Mithöfer A, Rayapuram N, Hirt H.   +6 more
europepmc   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Advanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot, Sebastian Jung, Sébastien Harlepp, Alexandre Detappe   +3 more
wiley   +1 more source

Multifunctional Wound Dressings: Melt Electrowritten Scaffolds Combined With Phytotherapeutic Composite Hydrogels

Advanced Materials Interfaces, EarlyView.
ABSTRACT The increasing prevalence of impaired wounds, caused mainly by diabetes or aging, alongside the growing number of bacterial infections, indicates the need for alternative tissue engineering solutions. In this study, we developed novel melt electrowritten (MEW) polycaprolactone (PCL) scaffolds incorporated with an alginate (Alg)–gelatin (Gel ...
Andrada‐Ioana Damian‐Buda, Aldo Roberto Boccaccini, Irem Unalan   +2 more
wiley   +1 more source