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The Turing heritage for plant biology: all spots and stripes?
Quantitative Plant BiologyIn ‘The chemical basis of morphogenesis’ (1952), Alan Turing introduced an idea that revolutionised our thinking about pattern formation. He proposed that diffusion could lead to the spontaneous formation of regular patterns.
Eric Siero, Eva E. Deinum
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Localized Coherent Structures and Patterns Formation in Collective Models of Beam Motion [PDF]
, 2000 Antonina N. Fedorova, Michael G. Zeitlin
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
PARAMETRIC DESIGN OF 3D PRINTED RIBBED SLAB SYSTEM BASED ON NATURE-INSPIRED PATTERNS
Facta Universitatis. Series: Architecture and Civil EngineeringThe interest in pattern geometry and its application to architecture may be seen throughout history. While some authors were fascinated by pattern aesthetics, others were focused on their effectiveness and underlying principles of pattern formation.
Maša Žujović, Jelena Milošević
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Stability of coherent pattern formation through invasion in the FitzHugh-Nagumo system [PDF]
, 2023 Montie Avery +3 more
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