Results 101 to 110 of about 1,192,191 (268)

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Matching of lateral cephalograms by means of similarity coefficients

open access: yesAustralasian Orthodontic Journal, 1986
This was a pilot study to establish the possible applications of taxonomic methods (taxonomy = study of the general principles of classification) to the identification of individuals.
Seliga Michelle E.   +2 more
doaj   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Full-fledged Real-Time Indexing for Constant Size Alphabets

open access: yes, 2013
In this paper we describe a data structure that supports pattern matching queries on a dynamically arriving text over an alphabet ofconstant size. Each new symbol can be prepended to $T$ in O(1) worst-case time.
Kucherov, Gregory, Nekrich, Yakov
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

On Tree Pattern Matching by Pushdown Automata

open access: yesActa Polytechnica, 2009
Tree pattern matching is an important operation in Computer Science on which a number of tasks such as mechanical theorem proving, term-rewriting, symbolic computation and non-procedural programming languages are based on.
T. Flouri
doaj  

Hardware acceleration of DNA pattern matching using analog resistive CAMs

open access: yesFrontiers in Electronics
DNA pattern matching is essential for many widely used bioinformatics applications. Disease diagnosis is one of these applications since analyzing changes in DNA sequences can increase our understanding of possible genetic diseases. The remarkable growth
Jinane Bazzi   +5 more
doaj   +1 more source

The dynamics of pattern matching in camouflaging cuttlefish. [PDF]

open access: yesNature, 2023
Woo T   +6 more
europepmc   +1 more source

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