Results 101 to 110 of about 284,765 (244)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Improved indoor localization using k‐medoids and k‐nearest neighbour algorithms with context similarity coefficient‐based fingerprint similarity metric

The Journal of Engineering
Fingerprint database clustering and localization using k‐medoids and k‐nearest neighbour (k‐NN) algorithms respectively typically use distance‐based fingerprint similarity metrics, with their performances dependent on the type of distance metric used ...
Abdulmalik Shehu Yaro, Filip Maly, Karel Maly, Pavel Prazak   +3 more
doaj   +1 more source

Shifting decision thresholds can undermine the probative value and legal utility of forensic pattern-matching evidence. [PDF]

Proc Natl Acad Sci U S A, 2023
Thompson WC.
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Multivariate Constrained Elastic Matching With Application in Real-Time Energy Disaggregation

IEEE Open Journal of the Computer Society
Non-Intrusive Load Monitoring (NILM) aims to estimate the power consumption of electrical appliances from the aggregated power consumption. While recent machine learning approaches have demonstrated very high disaggregation accuracies, ensuring real-time
Pascal A. Schirmer, Dimitrios Kolosov, Iosif Mporas   +2 more
doaj   +1 more source

Lightweight Pattern Matching Method for DNA Sequencing in Internet of Medical Things. [PDF]

Comput Intell Neurosci, 2022
Rexie JAM, Raimond K, Murugaaboopathy M, Brindha D, Mulugeta H.   +4 more
europepmc   +1 more source

Two-Phase PFAC Algorithm for Multiple Patterns Matching on CUDA GPUs [PDF]

, 2019
Wei-Shen Lai, Chao‐Chin Wu, Lien-Fu Lai, Min-Chi Sie   +3 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Pattern matching for high precision detection of LINE-1s in human genomes. [PDF]

BMC Bioinformatics, 2022
Lopez JO, Seguel J, Chamorro A, Ramos KS.   +3 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source