Results 101 to 110 of about 548,043 (300)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Feature selection for emotion recognition in speech: a comparative study of filter and wrapper methods [PDF]
PeerJ Computer ScienceFeature selection is essential for enhancing the performance and reducing the complexity of speech emotion recognition models. This article evaluates various feature selection methods, including correlation-based (CB), mutual information (MI), and ...
Alaa Altheneyan, Aseel Alhadlaq
doaj +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Improving the robustness of the usual fbe-based asr front-end [PDF]
, 2000 All speech recognition systems require some form of signal representation that parametrically models the temporal evolution of the spectral envelope. Current parameterizations involve, either explicitly or implicitly, a set of energies from frequency ...
Hernando Pericás, Francisco Javier +2 more
core
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Automatic voice recognition using traditional and artificial neural network approaches [PDF]
The main objective of this research is to develop an algorithm for isolated-word recognition. This research is focused on digital signal analysis rather than linguistic analysis of speech.
Botros, Nazeih M.
core +1 more source
A Hybrid Rough Sets K-Means Vector Quantization Model For Neural Networks Based Arabic Speech Recognition [PDF]
, 2002 Speech is a natural, convenient and rapid means of human communication. The abil ity to respond to spoken language is of special importance in computer application wherein the user cannot use his/her limbs in a proper way, and may be useful in office ...
Babiker, Elsadig Ahmed Mohamed
core
Learning Sparse Adversarial Dictionaries For Multi-Class Audio Classification
, 2017 Audio events are quite often overlapping in nature, and more prone to noise than visual signals. There has been increasing evidence for the superior performance of representations learned using sparse dictionaries for applications like audio denoising ...
Bhattacharya, Puranjoy, Shaj, Vaisakh
core +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source