Results 81 to 90 of about 545,718 (303)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

An investigation of potential applications of OP-SAPS: Operational Sampled Analog Processors [PDF]

open access: yes
The application of OP-SAP's (operational sampled analog processors) in pattern recognition system is summarized. Areas investigated include: (1) human face recognition; (2) a high-speed programmable transversal filter system; (3) discrete word (speech ...
Mcvey, E. S., Parrish, E. A.
core   +1 more source

Speaker Independent Speech Recognition Using Neural Network [PDF]

open access: yes, 2004
In spite of the advances accomplished throughout the last few decades, automatic speech recognition (ASR) is still a challenging and difficult task when the systems are applied in the real world.
Tan, Chin Luh
core  

Multimodal person recognition for human-vehicle interaction [PDF]

open access: yes, 2006
Next-generation vehicles will undoubtedly feature biometric person recognition as part of an effort to improve the driving experience. Today's technology prevents such systems from operating satisfactorily under adverse conditions.
Abut, Huseyin   +9 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Hidden Markov Models for Spatio-Temporal Pattern Recognition and Image Segmentation [PDF]

open access: yes, 2003
Time and again hidden Markov models have been demonstrated to be highly effective in one-dimensional pattern recognition and classification problems such as speech recognition.
Lovell, Brian C.
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Likelihood-based semi-supervised model selection with applications to speech processing

open access: yes, 2009
In conventional supervised pattern recognition tasks, model selection is typically accomplished by minimizing the classification error rate on a set of so-called development data, subject to ground-truth labeling by human experts or some other means.
Khudanpur, Sanjeev P.   +2 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Relating hearing loss and executive functions to hearing aid users’ preference for, and speech recognition with, different combinations of binaural noise reduction and microphone directionality

open access: yesFrontiers in Neuroscience, 2014
Knowledge of how executive functions relate to preferred hearing aid (HA) processing is sparse and seemingly inconsistent with related knowledge for speech recognition outcomes. This study thus aimed to find out if (1) performance on a measure of reading
Tobias eNeher
doaj   +1 more source

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