Results 61 to 70 of about 2,773,097 (263)

The GSK3/Shaggy-like kinase ASKα contributes to pattern-triggered immunity in Arabidopsis thaliana [PDF]

Plant Physiology, 2016
The first layer of immunity against pathogenic microbes relies on the detection of conserved pathogen-associated molecular patterns (PAMPs) that are recognized by pattern recognition receptors (PRRs) to activate pattern-triggered immunity (PTI). Despite the increasing knowledge of early PTI signaling mediated by PRRs and their associated proteins, many
Stampfl, Hansjörg, Fritz, Marion, DAL SANTO, SILVIA, Jonak, Claudia   +3 more
openaire   +3 more sources

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Unseen Struggles: How Plant-Parasitic Nematodes Manipulate ROS Signaling in Host Plants

Molecular Plant-Microbe Interactions
Reactive oxygen species (ROS) play a central role in plant defense, especially during interactions with plant-parasitic nematodes (PPNs). These molecules act as early signals that activate immune responses and help reinforce plant cell walls to block ...
Anil Kumar, Chunoti Changwal, Thomas J. Baum   +2 more
doaj   +1 more source

Host-induced bacterial cell wall decomposition mediates pattern-triggered immunity in Arabidopsis

eLife, 2014
Peptidoglycans (PGNs) are immunogenic bacterial surface patterns that trigger immune activation in metazoans and plants. It is generally unknown how complex bacterial structures such as PGNs are perceived by plant pattern recognition receptors (PRRs) and
Xiaokun Liu, Heini M Grabherr, Roland Willmann, Dagmar Kolb, Frédéric Brunner, Ute Bertsche, Daniel Kühner, Mirita Franz-Wachtel, Bushra Amin, Georg Felix, Marc Ongena, Thorsten Nürnberger, Andrea A Gust   +12 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Unlocking Nature's Defense: Plant Pattern Recognition Receptors as Guardians Against Pathogenic Threats

Molecular Plant-Microbe Interactions
Embedded in the plasma membrane of plant cells, receptor kinases (RKs) and receptor proteins (RPs) act as key sentinels, responsible for detecting potential pathogenic invaders.
Chao Zhang, Yingpeng Xie, Ping He, Libo Shan   +3 more
doaj   +1 more source

Enhancing crop innate immunity: new promising trends

Frontiers in Plant Science, 2014
Plants are constantly exposed to potentially pathogenic microbes present in their surrounding environment. Due to the activation of the pattern-triggered immunity (PTI) response that largely relies on accurate detection of pathogen- or microbe-associated
Pin-Yao eHuang, Laurent eZimmerli
doaj   +1 more source

Transcriptomic analysis reveals tomato genes whose expression is induced specifically during effector-triggered immunity and identifies the Epk1 protein kinase which is required for the host response to three bacterial effector proteins [PDF]

, 2014
Plants have two related immune systems to defend themselves against pathogen attack. Initially,pattern-triggered immunity is activated upon recognition of microbe-associated molecular patterns by pattern recognition receptors. Pathogenic bacteria deliver
Dunham, Diane M., Diane M Dunham, Yi Zheng, Zheng, Yi, Pombo, Marina A., Martin, Gregory B., Marina A Pombo, Zhangjun Fei, Gregory B Martin, Noe Fernandez-Pozo, Fernández-Pozo, Noé, Fei, Zhangjun   +11 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source