Results 21 to 30 of about 401,108 (305)

Maintenance of cell type-specific connectivity and circuit function requires Tao kinase

open access: yesNature Communications, 2019
It is unclear how circuit specificity and function are maintained during organismal growth. In this study, authors show that connectivity between primary nociceptors and their downstream neurons scales with animal size and that Ste20-like kinase Tao acts
Federico Marcello Tenedini   +13 more
doaj   +1 more source

Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion

open access: yeseLife, 2016
Formation of a regularly branched blood vessel network is crucial in development and physiology. Here we show that the expression of the Notch ligand Dll4 fluctuates in individual endothelial cells within sprouting vessels in the mouse retina in vivo and
Benedetta Ubezio   +8 more
doaj   +1 more source

Interactive manipulation of microparticles in an octagonal sonotweezer [PDF]

open access: yes, 2013
An ultrasonic device for micro-patterning and precision manipulation of micrometre-scale particles is demonstrated. The device is formed using eight piezoelectric transducers shaped into an octagonal cavity.
Beeley, J.   +4 more
core   +1 more source

Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1

open access: yeseLife, 2019
The cAMP-dependent protein kinase A (PKA) regulates various cellular functions in health and disease. In endothelial cells PKA activity promotes vessel maturation and limits tip cell formation.
Xiaocheng Zhao   +8 more
doaj   +1 more source

Two-Phase Lineage Specification of Telencephalon Progenitors Generated From Mouse Embryonic Stem Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
Proper brain development requires precisely controlled phases of stem cell proliferation, lineage specification, differentiation, and migration. Lineage specification depends partly on concentration gradients of chemical cues called morphogens.
Makoto Nasu   +4 more
doaj   +1 more source

Patterned Nanomagnetic Films [PDF]

open access: yes, 2006
Nano-fabrication technologies for realising patterned structures from thin films are reviewed. A classification is made to divide the patterning technologies in two groups namely with and without the use of masks. The more traditional methods as well as
Lodder, J.C.
core   +2 more sources

Intrinsic noise profoundly alters the dynamics and steady state of morphogen-controlled bistable genetic switches [PDF]

open access: yes, 2016
During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guide this process.
Briscoe, James   +3 more
core   +5 more sources

RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins [PDF]

open access: yes, 2016
The sea urchin larval skeleton offers a simple model for formation of developmental patterns. The calcium carbonate skeleton is secreted by primary mesenchyme cells (PMCs) in response to largely unknown patterning cues expressed by the ectoderm.
Bardot, Evan   +26 more
core   +1 more source

The transcription factors BEL1 and SPL are required for cytokinin and auxin signaling during ovule development in Arabidopsis [PDF]

open access: yes, 2012
Hormones, such as auxin and cytokinin, are involved in the complex molecular network that regulates the coordinated development of plant organs. Genes controlling ovule patterning have been identified and studied in detail; however, the roles of auxin ...
Bencivenga, Stefano   +3 more
core   +3 more sources

Bioelectricity in Developmental Patterning and Size Control: Evidence and Genetically Encoded Tools in the Zebrafish Model

open access: yesCells, 2023
Developmental patterning is essential for regulating cellular events such as axial patterning, segmentation, tissue formation, and organ size determination during embryogenesis.
Martin R. Silic, GuangJun Zhang
doaj   +1 more source

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