Results 31 to 40 of about 21,995 (240)

Introducing the rubber plate impact method: a versatile alternative to close proximity test for tire-pavement noise characterization on asphalt highways

open access: yesDiscover Civil Engineering
Despite its widespread use, the close proximity (CPX) test for tire-pavement noise is limited to existing pavements, posing challenges for timely and effective corrections of noisy pavements. Additionally, the CPX test entails significant procurement and
Jin Hwan Kim   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An Exploration of Recent Intelligent Image Analysis Techniques for Visual Pavement Surface Condition Assessment

open access: yesSensors, 2022
Road pavement condition assessment is essential for maintenance, asset management, and budgeting for pavement infrastructure. Countries allocate a substantial annual budget to maintain and improve local, regional, and national highways.
Waqar S. Qureshi   +6 more
doaj   +1 more source

Difference between Pavement Thickness Design and Pavement Life Prediction for Rigid Aircraft Pavements [PDF]

open access: yesDesigns, 2022
Aircraft pavements are generally designed using deterministic methods and using conservatively selected input parameter values, which combine to result in a low probability of structural failure occurring during the structural design life of the pavement.
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Chemo-mechanical characterization and data-driven correlation analysis of rejuvenated bitumen via artificial neural network

open access: yesMaterials & Design
The chemo-mechanical properties of bitumen undergo significant alternations during aging and rejuvenation, posing challenges for accurately evaluating and enhancing rejuvenation efficiency in asphalt recycling. This study investigates how bitumen source,
Shisong Ren   +4 more
doaj   +1 more source

Quantification of skid resistance seasonal variation in asphalt pavements

open access: yesJournal of Traffic and Transportation Engineering (English ed. Online), 2020
The present study deals with the quantification of skid resistance seasonal variation in asphalt pavements. Consequently, skid resistance data were collected twice per year (after “wet” and “dry” seasons) along four trial sections of an urban highway ...
Christina Plati   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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