Results 51 to 60 of about 112,983 (304)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Pavement Diagnosis as Integrant of the Pavement Management System [PDF]

Communications - Scientific letters of the University of Zilina, 2008
The paper integrates the most important scientific information of the authors in the field of diagnostics of road pavements. Basic attributes of pavement serviceability (evenness, skid resistance) and pavement bearing capacity are the core of the paper. The results of simulations of dynamic systems, outputs of the models developed at the authors place,
Jan Celko, Martin Decky, Jozef Komacka, Matus Kovac   +3 more
openaire   +2 more sources

MEPDG Work Plan Task No. 7: Existing Pavement Input Information for the Mechanistic-Empirical Pavement Design Guide, 2009 [PDF]

, 2009
The objective of this study is to systematically evaluate the Iowa Department of Transportation’s (DOT’s) existing Pavement Management Information System (PMIS) with respect to the input information required for Mechanistic-Empirical Pavement Design ...

core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Corrigendum: The use of reflective and permeable pavements as a potential practice for heat island mitigation and stormwater management

Environmental Research Letters, 2013
The full text of this article is available in the PDF provided.
H Li, J T Harvey, T J Holland, M Kayhanian   +3 more
doaj   +1 more source

Strategic Plan for Improved Concrete Pavement Surface Characteristics, July 2006 [PDF]

, 2006
Surface characteristics represent a critical issue facing pavement owners and the concrete paving industry. The traveling public has come to expect smoother, quieter, and better drained pavements, all without compromising safety.

core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Automated Pavement Condition Assessment Using Laser Crack Measurement System (LCMS) on Airfield Pavements in Ireland [PDF]

, 2015
Pavement condition surveys which identify pavement distress types, severities and quantities and provide a condition index or rating are an essential part of any pavement management system and an invaluable tool in the evaluation of a pavement's ...
O'Brien, David A., Mulry, Brian, Jordan, Michael   +2 more
core  

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

The Influence of Statistical Spatial Repeatabiliy on Remaining Pavement Life [PDF]

, 2012
6th International Conference on Computational Stochastic Mechanics (CSM-6), Rhodos, Greece, June 13-16, 2010A road develops permanent deformation and fatigue damage because of the strains induced in its structure by surface loading and environmental ...
O'Brien, Eugene J., Taheri, A.
core   +1 more source