Results 71 to 80 of about 273,956 (307)

Estimating the Application Rate of Liquid Chloride Products Based on Residual Salt Concentration on Pavement [PDF]

open access: yes, 2018
This technical report summarizes the results of laboratory testing on asphalt and concrete pavement. A known quantity of salt brine was applied as an anti-icer, followed by snow application, traffic simulation, and mechanical snow removal via simulated ...
Akin, Michelle   +2 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Bumpy Roads Ahead: America's Roughest Rides and Strategies to Make our Roads Smoother [PDF]

open access: yes, 2013
These days, potholes and pavement deterioration make it a challenge to keep the wheel steady on America's roads and highways. More than a quarter of the nation's major urban roadways -- highways and major streets that are the main routes for commuters ...

core  

The effect of pavement-watering on subsurface pavement temperatures [PDF]

open access: yesUrban Climate, 2015
Abstract Pavement-watering is currently viewed as a potential climate change adaptation and urban heat island mitigation technique. The effects of pavement-watering on pavement temperature measured 5 cm deep are presented and discussed. Subsurface temperature measurements could not be used to improve or optimize pavement-watering methods as was seen ...
Hendel, Martin, Royon, Laurent
openaire   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Public Perceptions of the Midwest’s Pavements - Iowa - Phase III [PDF]

open access: yes, 2001
There are several objectives to this report. The first objective is to describe the sample with regard to the physical pavement data and three measures of driver satisfaction.
Giese, James K.   +4 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

An Empirical Model for Optimal Highway Durability in Cold Regions [PDF]

open access: yes, 2016
We develop an empirical tool to estimate optimal highway durability in cold regions. To test the model, we assemble a data set containing all highway construction and maintenance projects in Arizona and Washington State from 1990 to 2014.
Yan, Jia
core  

A New Materials and Design Approach for Roads, Bridges, Pavement, and Concrete [PDF]

open access: yes, 2020
Increased understanding of demand for transport energy and how to improve road pavement materials would enable decision makers to make environmental, financial, and other positive changes in future planning and design of roads, bridges, and other ...
Acharya, Tathagata   +4 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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