Results 71 to 80 of about 493,639 (383)
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Structural Performance Assessment of Airfield Concrete Pavements Based on Field and Laboratory Data
Infrastructures, 2021 Maintenance interventions and rehabilitation actions in airfield pavements are time-consuming and adversely affect pavements’ serviceability (i.e., airport closures), with a profound impact on the airport economics.
Konstantinos Gkyrtis +3 more
doaj +1 more source
Public Perceptions of the Midwest’s Pavements - Iowa - Phase III [PDF]
, 2001 There are several objectives to this report. The first objective is to describe the sample with regard to the physical pavement data and three measures of driver satisfaction.
Giese, James K. +4 more
core +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Applied SciencesThis study aims to evaluate the tire–road-wear particles (TRWPs) and suspended dust generated based on the nominal maximum aggregate size (NMAS) of the polymer-modified stone mastic asphalt (SMA) mixtures indoors.
Jongsub Lee +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Materials & DesignRejuvenators are crucial for efficient asphalt pavement recycling, but their effectiveness varies widely based on factors like bitumen source, aging degree, and rejuvenator composition.
Shisong Ren +3 more
doaj +1 more source
Non-Newtonian Behaviors of Crumb Rubber-Modified Bituminous Binders
Applied Sciences, 2018 Crumb rubber-modified bitumen (CRMB) has been utilized in the asphalt paving industry for decades due to its various benefits. The complex interaction between bitumen and crumb rubber as well as the addition of warm-mix additives makes the typical laws ...
Haopeng Wang +3 more
doaj +1 more source
DESIGN AND PROPERTIES OF HOT MIXTURE POROUS ASPHALT FOR SEMI-FLEXIBLE PAVEMENT APPLICATIONS [PDF]
, 2005 Semi-flexible pavement consists of selected porous asphalt mixture filled with cementitious slurry. This new type of pavement has prospects to be designed as a high deformation resistant pavement (Setyawan et al, 2001).
Setyawan, Ary
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source