Results 41 to 50 of about 13,570,973 (355)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Investigation of Feasible Pavement Design Alternatives for WisDOT [PDF]
, 1999 The current pavement design and selection process of WisDOT for all new pavements or reconstructions of existing pavement structures provides for the design of one asphaltic concrete (AC) and one portland cement concrete (PCC) pavement alternative.
Crovetti, James, Owusu-Ababio, Sam
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
مجلة النهرين للعلوم الهندسيةFlexible and rigid pavements are commonly built for airport pavements to support the moving loads of aircraft during the pavement design life. Airport pavements represent a cornerstone of the aviation world.
Mustafa I. Ahmed, Alaa H. Abed
doaj +1 more source
Green Up Pavement Rehabilitation Design Tool [PDF]
, 2019 While designers produce pavement rehabilitation recommendations every day, for projects of all sizes, most designers have little information on the environmental impact of their recommendations.
Andrei, Dragos +2 more
core +1 more source
A New Materials and Design Approach for Roads, Bridges, Pavement, and Concrete [PDF]
, 2020 Increased understanding of demand for transport energy and how to improve road pavement materials would enable decision makers to make environmental, financial, and other positive changes in future planning and design of roads, bridges, and other ...
Acharya, Tathagata +4 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Design and Sustainability Aspects of Geogrid-Reinforced Flexible Pavements—An Indian Perspective
Frontiers in Built Environment, 2020 Design of flexible pavements is not straightforward when reinforcement materials such as geogrid, geocell, and other types of geosynthetic materials are used in pavement construction.
G. Narendra Goud +5 more
doaj +1 more source
Geotechnics, 2022 Pavement thickness is a very vital component during the design stage of a road construction project. Pavement design helps to determine the costs of the project over a certain period to ascertain how the cost of road pavement construction affect the life
Samuel Y. O. Amakye +2 more
doaj +1 more source