Results 41 to 50 of about 148,698 (312)
Pavement Design for Curved Road Sections: Fatigue Performance of Interfaces and Longitudinal Top-down Cracking in Multilayered Pavements [PDF]
, 2009 International audienceThis paper focuses on damage processes other than the main one observed and studied in pavement design. Previous research has targeted the experimental fatigue performance of tack coats.
Diakhaté, Malick +4 more
core +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Pavement Analysis with the Consideration of Unbound Granular Material Nonlinearity
Designs, 2023 Accurate pavement design and evaluation requires the execution of response analysis. Pavement materials’ behavior does not necessarily conform to the assumptions of the multi-linear elastic theory usually adopted during pavement analysis.
Konstantinos Gkyrtis
doaj +1 more source
Structural Design Guidelines for Pervious Concrete Pavements [PDF]
, 2019 Pervious pavements have gained popularity in recent years as the transportation industry focuses on sustainability and environmental impact. This research investigated the structural design of pervious concrete pavements.
Smith, April
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
مجلة النهرين للعلوم الهندسيةFlexible and rigid pavements are commonly built for airport pavements to support the moving loads of aircraft during the pavement design life. Airport pavements represent a cornerstone of the aviation world.
Mustafa I. Ahmed, Alaa H. Abed
doaj +1 more source
Green Up Pavement Rehabilitation Design Tool [PDF]
, 2019 While designers produce pavement rehabilitation recommendations every day, for projects of all sizes, most designers have little information on the environmental impact of their recommendations.
Andrei, Dragos +2 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Life cycle analysis of road construction and use [PDF]
, 2019 Both the construction and use of roads have a range of environmental impacts; therefore, it is important to assess the sources of their burdens to adopt correct mitigation policies.
D'Andrea, Antonio +2 more
core +1 more source