Results 41 to 50 of about 27,219 (315)
مجلة النهرين للعلوم الهندسيةFlexible and rigid pavements are commonly built for airport pavements to support the moving loads of aircraft during the pavement design life. Airport pavements represent a cornerstone of the aviation world.
Mustafa I. Ahmed, Alaa H. Abed
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
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Pavement design guidelines [PDF]
, 2008 The purpose of pavement design activity is to provide the most cost-effective pavement structure while optimizing the level of service provided to road users.
South Carolina Department of Transportation Office of Materials and Research Pavement Design Unit
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
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Heliyon, 2018 With the advancement in pavement design and performance analysis procedures, the coefficient of thermal expansion (CTE) of concrete has emerged as a significant design input with a direct impact on concrete pavement performance parameters including ...
Gauhar Sabih +2 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
ANALYSIS OF ROAD DAMAGE DUE TO OVER LOADING (CASE STUDY: DEMAK -TRENGGULI ARTERIAL ROAD, CENTRAL JAVA PROVINCE, INDONESIA) [PDF]
, 2011 The ability of a pavement structure in carrying out its function reduces in line with the increase of traffic load, especially if there are overloaded heavy vehicle passing through the road.
Abobaker Ali Langer, Ibrahim
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