Results 81 to 90 of about 146,603 (293)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Characterization of Asphalt Treated Base Course Material [PDF]
INE/AUTC 11 ...
Li, Peng, Liu, Juanyu
core
Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou +12 more
wiley +1 more source
Quarter car active suspension system design using optimal and robust control method [PDF]
This paper offers with the theoretical and computational evaluation of optimal& robust controlproblems, with the goal of providing answers to them with MATLAB simulation.For the robust control, -synthesis controller and for the ...
Jibril, Mustefa
core +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Design of Rigid Pavements in Iowa Using the Mechanistic-Empirical Pavement Design Guide
The Iowa Dept of Transportation (DOT) currently utilizes the empirically-based American Association of State Highway and Transportation Officials (AASHTO) pavement design procedures originally derived from the 1960 Road Test data. It is clear that these empirical procedures are no longer applicable to current conditions in Iowa. With the release of the
Ceylan, Halil +2 more
openaire +4 more sources
Prediction of Thermal Behavior of Pervious Concrete Pavements in Winter [PDF]
Because application of pervious concrete pavement (PCPs) has extended to cold-climate regions of the United States, the safety and mobility of PCP installations during the winter season need to be maintained.
Chen, Zhao +3 more
core
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Generation of traffic input for flexible pavement design. [PDF]
Richard F, Mpele M.
europepmc +1 more source
Standardized Testing of Non-Standard Photovoltaic Pavement Surfaces [PDF]
Emerging photovoltaic products have expanded the applications for the technologies into markets previously unconsidered for what was thought to be a delicate electronic product.
Coutu, Ronald A., Jr. +2 more
core +2 more sources

