Results 81 to 90 of about 146,603 (293)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Characterization of Asphalt Treated Base Course Material [PDF]

open access: yes, 2010
INE/AUTC 11 ...
Li, Peng, Liu, Juanyu
core  

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou   +12 more
wiley   +1 more source

Quarter car active suspension system design using optimal and robust control method [PDF]

open access: yes, 2020
This paper offers with the theoretical and computational evaluation of optimal& robust controlproblems, with the goal of providing answers to them with MATLAB simulation.For the robust control, -synthesis controller and for the ...
Jibril, Mustefa
core   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Design of Rigid Pavements in Iowa Using the Mechanistic-Empirical Pavement Design Guide

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2008
The Iowa Dept of Transportation (DOT) currently utilizes the empirically-based American Association of State Highway and Transportation Officials (AASHTO) pavement design procedures originally derived from the 1960 Road Test data. It is clear that these empirical procedures are no longer applicable to current conditions in Iowa. With the release of the
Ceylan, Halil   +2 more
openaire   +4 more sources

Prediction of Thermal Behavior of Pervious Concrete Pavements in Winter [PDF]

open access: yes, 2017
Because application of pervious concrete pavement (PCPs) has extended to cold-climate regions of the United States, the safety and mobility of PCP installations during the winter season need to be maintained.
Chen, Zhao   +3 more
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Standardized Testing of Non-Standard Photovoltaic Pavement Surfaces [PDF]

open access: yes, 2016
Emerging photovoltaic products have expanded the applications for the technologies into markets previously unconsidered for what was thought to be a delicate electronic product.
Coutu, Ronald A., Jr.   +2 more
core   +2 more sources

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