Results 31 to 40 of about 29,164 (316)

Predicting Rutting Development of Pavement with Flexible Overlay Using Artificial Neural Network

Applied Sciences, 2023
Pavement maintenance and repair is a crucial part of pavement management systems. Accurate and reliable pavement performance prediction is the prerequisite for making reasonable maintenance decisions and selecting suitable repair schemes.
Chunru Cheng, Chen Ye, Hailu Yang, Linbing Wang   +3 more
doaj   +1 more source

Performance of Warranted Asphalt Pavements: Smoothness and Performance of Indiana Warranted Asphalt Pavements

, 2016
In the early 1990s the Indiana Department of Transportation (INDOT) developed a five-year warranty specification for asphalt pavements with the first project being built in 1996. In 2004, results indicated that the asphalt pavements built with the warranty specification had improved performance over the conventional asphalt pavements.
Leila Sadeghi, Rebecca McDaniel, John Haddock   +2 more
openaire   +2 more sources

EVALUATION PAVEMENT DISTRESSES USING PAVEMENT CONDITION INDEX [PDF]

, 2011
Pavement deterioration is resulted by both environmental and structural causes. It is difficult to maintain the road on the same specification that was owned at the opening and problems start to appear represented in the pavement cracks, holes and ...
ZALTUOM, ALI MOHAMED ALI, kushardjoko, wahyudi, Yulipriyono, Eko   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Assessing reinforced pavement performance: Influence of geogrid position, axial stiffness, and applied stress

CTU Journal of Innovation and Sustainable Development
This study examined the performance of pavement, considering geogrid’s position within the pavement layers, geogrid’s axial stiffness, and applied stress through the Plaxis 2D program.
Tan-Hung Nguyen, Kyra Kamille A. Toledo, Trong Phuoc Huynh   +2 more
doaj   +3 more sources

Performance improvement model of cement pavement in seasonal-frost regions

Magazine of Civil Engineering, 2022
To effectively evaluate the performance improvement of cement pavement in seasonal frost regions, the typical diseases of cement concrete pavements in seasonal frost regions are proposed through the analysis of measured data, and the influence factors of
Zhao Qianqian, Fu Qiang, Zhang Hetong, Wang Jianwu   +3 more
doaj   +1 more source

The hydrological performance of a permeable pavement [PDF]

Urban Water Journal, 2010
Urban stormwater runoff is a transport medium for many contaminants from anthropogenic sources. There are many alternative management strategies available to treat these contaminants. One of the technologies suggested for this purpose is the use of permeable pavements to minimise the quantity of surface runoff generated by impervious surfaces within an
J. E. Ball, K. Rankin
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source