Results 71 to 80 of about 133,577 (291)

Characterization of Asphalt Treated Base Course Material [PDF]

open access: yes, 2010
INE/AUTC 11 ...
Li, Peng, Liu, Juanyu
core  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Research and comparison of pavement performance prediction based on neural networks and fusion transformer architecture

open access: yesElectronic Research Archive
The decision-making process for pavement maintenance from a scientific perspective is based on accurate predictions of pavement performance. To improve the rationality of pavement performance indicators, comprehensive consideration of various influencing
Hui Yao   +4 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Modeling Pavement Performance Based on LTPP Database for Flexible Pavements

open access: yesTeknik Dergi, 2020
In many countries, incredible investments have been made in constructing roads that require conducting periodic evaluation and timely maintenance and rehabilitation (M&R) plan to keep the network operating under acceptable level of service.
Mostafa RADWAN   +3 more
openaire   +3 more sources

Bumpy Roads Ahead: America's Roughest Rides and Strategies to Make our Roads Smoother [PDF]

open access: yes, 2013
These days, potholes and pavement deterioration make it a challenge to keep the wheel steady on America's roads and highways. More than a quarter of the nation's major urban roadways -- highways and major streets that are the main routes for commuters ...

core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Software development for flexible pavement thickness design based on aastho and road note 31 [PDF]

open access: yes, 2009
Nowadays, road and surface failure has become a critical issue in our country on the flexible pavement which reflects to a bad quality and error during design stage.
Chang, Tun Hua
core  

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Smartphone-Based Cost-Effective Pavement Performance Model Development Using a Machine Learning Technique with Limited Data

open access: yesInfrastructures
Road networks play a significant role in each country’s economy, especially in countries such as Afghanistan, which is strategically located in the international transit path from Europe to East Asia.
Samiulhaq Wasiq, Amir Golroo
doaj   +1 more source

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