Results 61 to 70 of about 135,271 (312)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Evaluation of Anti-icing Emulsified Asphalt Binders
Frontiers in Materials, 2020 Snow and ice on asphalt pavement surface can significantly affect traffic safety and damage pavements. To reduce its effect, a kind of anti-icing emulsified asphalt binder (AEAB) is developed by adding a certain amount of anti-icing fillers to the ...
Liyan Shan +3 more
doaj +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Investigation of AASHTOWare Pavement ME Design/DARWin-ME Performance Prediction Models for Iowa Pavement Analysis and Design, 2015 [PDF]
, 2015 The Mechanistic-Empirical Pavement Design Guide (MEPDG) was developed under National Cooperative Highway Research Program (NCHRP) Project 1-37A as a novel mechanistic-empirical procedure for the analysis and design of pavements.
core
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Journal of Traffic and Transportation Engineering (English ed. Online), 2019 Unbonded concrete overlay (UBCO) is the most used pavement rehabilitation technique across United States with an overall usage of 47% amongst all the rehabilitation methods. It is aimed to improve the performance of any deteriorated/cracked jointed plain
Gauhar Sabih, Rafiqul A. Tarefder
doaj +1 more source
Investigation of AASHTOWare Pavement ME Design/DARWin-MEPerformance Prediction Models for Iowa Pavement Analysis and Design [PDF]
, 2015 The Mechanistic-Empirical Pavement Design Guide (MEPDG) was developed under National Cooperative Highway Research Program (NCHRP) Project 1-37A as a novel mechanistic-empirical procedure for the analysis and design of pavements.
Ceylan, Halil +4 more
core +2 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Evaluation of the pavement performance
Bulletin of the Polish Academy of Sciences Technical Sciences, 2015 Abstract This paper focuses on evaluation of two laboratory-based methods of compaction of foamed bitumen and bitumen emulsion mixes: impact compaction with a Marshall hammer and static compaction using a hydraulic press. The investigated compaction methods were assessed in terms of their impact on the physical and mechanical properties of produced
M. Iwański, A. Chomicz-Kowalska
openaire +1 more source