Results 71 to 80 of about 135,271 (312)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
PERFORMANCE ENHANCEMENT OF ASPHALT PAVEMENT [PDF]
Al-Azhar Bulletin of Science- Basic Science Sector, 2013 Age hardening of paving grade asphalt is a major factor affecting the durability of bitumen pavement. In this research, 60/70 penetration grade asphalt is modified using Styrene Butadiene Rubber(SBR) in percentages by weight of asphalt ranging from 2 to 6% and 1% by weight of asphalt of an antioxidant namely 4.4.
openaire +1 more source
Bumpy Roads Ahead: America's Roughest Rides and Strategies to Make our Roads Smoother [PDF]
, 2013 These days, potholes and pavement deterioration make it a challenge to keep the wheel steady on America's roads and highways. More than a quarter of the nation's major urban roadways -- highways and major streets that are the main routes for commuters ...
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Modeling Pavement Performance Based on LTPP Database for Flexible Pavements
Teknik Dergi, 2020 In many countries, incredible investments have been made in constructing roads that require conducting periodic evaluation and timely maintenance and rehabilitation (M&R) plan to keep the network operating under acceptable level of service.
Mostafa RADWAN +3 more
openaire +3 more sources
Develop Guidelines for Pavement Preservation Treatments and for Building a Pavement Preservation Program Platform for Alaska [PDF]
, 2012 INE/AUTC 12 ...
Cheng, DingXin +4 more
core
Effect of Proportion of Missing Data on Application of Data Imputation in Pavement Management Systems [PDF]
, 2015 Missing data are commonly found in pavement condition/performance databases. A common practice today is to apply statistical imputation methods to replace the missing data with imputed values.
B. H. , Setiadji +2 more
core +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
InfrastructuresRoad networks play a significant role in each country’s economy, especially in countries such as Afghanistan, which is strategically located in the international transit path from Europe to East Asia.
Samiulhaq Wasiq, Amir Golroo
doaj +1 more source