BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Monthly Attenuation Prediction for Asphalt Pavement Performance by Using GM (1, 1) Model
Advances in Civil Engineering, 2019 Due to the uncertainty and variability of various factors affecting the pavement performance, the change in pavement performance cannot be completely determined.
Limin Tang, Duyang Xiao
doaj +1 more source
Performance of TenCate Paving Interlayers in Asphalt Concrete Pavements [PDF]
, 2017 As a continued effort of a previously completed project entitled “Performance of TenCate Mirafi PGM-G4 Interlayer-Reinforced Asphalt Pavements in Alaska,” this project evaluated two newly modified paving interlayers (TruPave and Mirapave) through overlay,
Li, Lin, Liu, Jenny, Zhao, Sheng
core
Investigation of Premature Distress Around Joints in PCC Pavements: Parts I & II [PDF]
, 2012 Some of the Indiana concrete pavements constructed within the last 10-20 years have shown signs of premature deterioration, especially in the areas adjacent to the longitudinal and transverse joints.
Arribas-Colón, Maria del Mar +3 more
core +2 more sources
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Develop Guidelines for Pavement Preservation Treatments and for Building a Pavement Preservation Program Platform for Alaska [PDF]
, 2012 INE/AUTC 12 ...
Cheng, DingXin +4 more
core
Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou +12 more
wiley +1 more source
Applied SciencesConcrete’s coefficient of thermal expansion (CTE) is a critical property affecting the durability and performance of rigid pavements. This review paper examines the significance of CTE in pavement design and the factors influencing it, including the type
Alka Subedi +3 more
doaj +1 more source
Prediction of Thermal Behavior of Pervious Concrete Pavements in Winter [PDF]
, 2017 Because application of pervious concrete pavement (PCPs) has extended to cold-climate regions of the United States, the safety and mobility of PCP installations during the winter season need to be maintained.
Chen, Zhao +3 more
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Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source