Results 31 to 40 of about 6,337 (198)

Drug-drug interaction with oral antivirals for the early treatment of COVID-19 [PDF]

, 2022
Non peer ...
Kovanen, Petri T., Raal, Frederick, Vuorio, Alpo   +2 more
core   +2 more sources

The efficacy of paxlovid in elderly patients infected with SARS-CoV-2 omicron variants: Results of a non-randomized clinical trial

Frontiers in Medicine, 2022
ObjectiveTo evaluate the efficacy of Paxlovid in treating Chinese elder patients infected with SARS-CoV-2 omicron variants.Materials and methodsWe performed a non-randomized, controlled trial in Shanghai, China.
Weijie Zhong, Xiufeng Jiang, Xiaosheng Yang, Tiantong Feng, Zhixin Duan, Wei Wang, Zhaoliang Sun, Lingyan Chen, Xin Nie, Chuanlong Zhu, Wenchuan Zhang, Yi Li   +11 more
doaj   +1 more source

Paxlovid–tacrolimus drug–drug interaction caused severe diarrhea that induced combined diabetic ketoacidosis and a hyperglycemic hyperosmolar state in a kidney transplant patient: a case report

Journal of Medical Case Reports, 2023
Background Transplant recipients are at high risk of coronavirus disease 2019, and a timely supply of antivirals should be prioritized for those patients.
Wei Luo, Yu He, Mao Gang Wei, Guang Bing Lu, Qun Yi   +4 more
doaj   +1 more source

Serotonin Syndrome Precipitated by Paxlovid Initiation

Cureus, 2023
A female in her early 40s taking buspirone, quetiapine, and daily kratom presented to the emergency department two days after starting a course of Paxlovid for a mild COVID-19 infection with diffuse tremors, ocular clonus, diaphoresis, and confusion consistent with serotonin syndrome (SS).
Nasser, Nicholas G, Welsh, Connor, Mitra, Avir, Swan, Matthew   +3 more
openaire   +2 more sources

Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2 [PDF]

, 2022
Three directly acting antivirals (DAAs) demonstrated substantial reduction in COVID-19 hospitalizations and deaths in clinical trials. However, these agents did not completely prevent severe illness and are associated with cases of rebound illness and ...
Aittokallio, Tero, Biering, Scott B., Gale, Michael, Herring, Shawn, Hoffmann, Markus, Hsiang, Tien-Ying, Ianevski, Aleksandr, Poehlmann, Stefan, Polyak, Stephen J., Schiffer, Joshua T., Wagoner, Jessica, White, Judith M., Xu, Shuang   +12 more
core   +2 more sources

The Use of Paxlovid Amongst the Elderly & Reduced Hospital Stays [PDF]

, 2023
Coronaviruses are a large family of viruses infecting many species and cause a variety of illnesses. COVID-19 is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS- CoV-2).
Ames, Kate, Chandler, Nicole, Gichana, Maria M, Gill, Madeline   +3 more
core   +1 more source

Absolute Risk Reductions in COVID-19 Antiviral Medication Clinical Trials

Pharmacoepidemiology, 2023
COVID-19 antiviral medications approved or authorized for emergency use by the U.S. Food and Drug Administration are reported to have high efficacy in preventing severe illness, hospitalizations, and deaths.
Ronald B. Brown
doaj   +1 more source

A Rare Case of Paxlovid-Induced Pancreatitis

Cureus, 2023
Acute pancreatitis can result secondary to an inflammatory cascade due to an insult to the pancreatic parenchyma, whether it be from infections, medications, etc. We present a case of a 37-year-old male with acute pancreatitis after being started on Paxlovid, a combination drug containing Nirmatrelvir and Ritonavir, for COVID-19 treatment.
Zaidi, Syed Muhammad Hussain, Iskander, Peter A, Ahmed, Khalid, Jaber, Fouad, Paz, Merlin, Khan, Ali, Malik, Fahad, Aloysius, Mark M   +7 more
openaire   +2 more sources

Real-world effectiveness of Yindan Jiedu granules-based treatment on patients infected with the SARS-CoV-2 Omicron variants BA.2 combined with high-risk factors: A cohort study

Frontiers in Pharmacology, 2022
Background: Our previous studies have shown that Yindan Jiedu granules (YDJDG) can effectively treat coronavirus disease 2019 (COVID-19); however, the high infectivity and the immune escape potential of the Omicron variant BA.2 make it more difficult to ...
Ying Feng, Yao Liu, Long Liu, Yao Liu, Yuyong Jiang, Yixin Hou, Yang Zhou, Rui Song, Xiaoyou Chen, Xianbo Wang   +9 more
doaj   +1 more source

Clinical efficacy analysis of paxlovid in children with hematological diseases infected with the omicron SARS-CoV-2 new variant

Frontiers in Pediatrics, 2023
ObjectiveTo summarize the clinical characteristics of children with hematological malignancies co-infected with novel coronavirus and explore the safety and effectiveness of Paxlovid treatment.MethodsFrom December 10, 2022, to January 20, 2023, the ...
Yixian Li, Yong Liu, Luping Wen, Hui Chen, Wenqing Wang, Mengyao Tian, Yucai Cheng, Hongman Xue, Chun Chen   +8 more
doaj   +1 more source