Results 141 to 150 of about 31,015 (257)

Problem-Based Learning (PBL) Model in Teaching Medical Laboratory Science at University of Hawai'i. [PDF]

Hawaii J Health Soc Welf
Nxedhlana V.
europepmc   +1 more source

Design, Synthesis, and Biological Evaluation of Chiral Urea and Thiourea Derivatives as Multitarget‐Directed Anti‐Alzheimer Agents

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A series of novel chiral urea and thiourea compounds were designed as multitarget‐directed ligands for Alzheimer's disease and evaluated against hAChE, hBChE, and hMAO‐B, with exploratory assessment of HSD10. These chiral compounds were synthesized and fully characterized, and their enantiopurity was confirmed via HPLC.
Sule Erol Gunal, Senel Teke Tuncel, İlke Demir, İpek Baysal, Gökçen Telli, Safiye Sag Erdem, Gulberk Ucar, Michaela Hanzlova, Kamil Musilek, İlknur Dogan, Nesrin Gokhan Kelekci   +10 more
wiley   +1 more source

A combined PBL and flipped classroom intervention enhances self-directed learning ability and empathy in ophthalmology undergraduates. [PDF]

Sci Rep
Yang Y, Xue J, Hu L, Fang K, Wei C, Wu C, Jin H.   +6 more
europepmc   +1 more source

Targeted Interventions in HAM/TSP: Emerging Therapies and Future Directions – A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aim Human T‐Lymphotropic virus type 1 (HTLV‐1) infection can lead to HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), a debilitating chronic neurological disease characterized by progressive lower limb spasticity and autonomic dysfunction.
Meygol Mirzaei Rezaei, Mahdi Khosravi Nia, Kasra Allaei Rouzbahani, Maryam Kazemi, Negar Asghari Hosori, Mehdi Norouzi, Farzaneh Sotoudegan, Narges Eslami, Negar Ariamand, Vahid Shahnavaz, Arash Letafati, Sayed‑Hamidreza Mozhgani   +11 more
wiley   +1 more source

Learner agency in a problem-based learning curriculum: A qualitative study on perspectives of undergraduate dental students. [PDF]

PLoS One
Gupta N, Sunil S, Ali K, Fink T, Du X.
europepmc   +1 more source

SARS‐CoV‐2 mRNA Vaccination Induces Neutralizing Antibodies and Type I IFN Changes in People Living With HIV

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT This study examined changes in anti‐Spike (anti‐S) antibodies (Abs) and type I interferon (IFN‐I) following the BNT162b2 vaccine in people living with HIV (PLWH) and analyzed the impact of demographic and immunological factors. In total, 75 PLWH and 28 healthy donors were followed at baseline (T0), at the second dose (T1), after the second ...
Federica Frasca, Luca Maddaloni, Alessandra D'Auria, Matteo Fracella, Ginevra Bugani, Carmen Falvino, Valentina Baccolini, Giuseppe Migliara, Francesca Aloisi, Letizia Santinelli, Enrico Palermo, Luca Bortolani, Alessandro Lazzaro, Giancarlo Ceccarelli, Ombretta Turriziani, Claudio Maria Mastroianni, Guido Antonelli, Gabriella d'Ettorre, Carolina Scagnolari   +18 more
wiley   +1 more source

Prognosis and treatment of plasmablastic lymphoma in the United States: a multicenter retrospective study. [PDF]

Blood Cancer J
Hamby M, Egleston BL, Frosch ZAK, Steiner RE, Noy A, Carvajal V, Chong ER, Tolu SS, Jean-Louis G, Amengual JE, Patel R, Ahmed S, Sharp J, Voorhees T, Baiocchi R, Ramirez-Gamero A, Castillo JJ, Hamburger E, Dittus C, Nizamuddin IA, Mehta-Shah N, Thaw Dar NN, Sandoval-Sus J, Rojek AE, Riedell PA, Khan N, Danilov A, Solipuram V, Rubinstein PG, Ariotti A, Suneja G, Vartanov A, Milrod C, Olszewski AJ, Smilnak G, Ayers E, Desai S, Rhodes JM, Magarelli G, Feldman T, Pellon M, Aboulafia DM, Bae W, Galvez C, Bhatlapenumarthi V, Hamadani M, Barta SK.   +46 more
europepmc   +1 more source

CCL20 Released by Drug–Tolerant Persisters Impairs Immunotherapy in EGFR–Mutant Lung Adenocarcinoma

MedComm, Volume 7, Issue 8, August 2026.
Schematic representation of tumor immune microenvironment (TIME) modulation by combined anti‐PD‐1 and anti‐CCL20 therapies. Left: In the “cold” tumor TIME, high CCL20 secretion by drug‐tolerant persister (DTP) cancer cell subpopulations promotes regulatory T cell (Treg) enrichment and clusters in close proximity to tumor cells, resulting in immune ...
Hoi‐Hin Kwok, Jiashuang Yang, Nerissa Chui‐Mei Lee, Junyang Deng, David Chi‐Leung Lam   +4 more
wiley   +1 more source

A novel Z-number based multi-stage assessment framework for problem-based learning in practical courses. [PDF]

PLoS One
Yu L, Chen Z, Qin Z.
europepmc   +1 more source

Taxonomic reappraisal of the mangrove genus Avicennia (Acanthaceae) in India

Nordic Journal of Botany, Volume 2026, Issue 8, August 2026.
A taxonomic reappraisal of the mangrove genus Avicennia in India was undertaken through extensive field surveys and critical examination of herbarium specimens. Three taxa, Avicennia alba, Avicennia marina subsp. marina, and Avicennia officinalis, are described in detail. A synonymic list was compiled using the World Checklist of Vascular Plants (WCVP)
Subrata Mondal, Saikat Naskar
wiley   +1 more source