Results 31 to 40 of about 90,682 (229)

Costs of avoiding net negative emissions under a carbon budget

Environmental Research Letters, 2021
The 2 °C and 1.5 °C temperature targets of the Paris Agreement can be interpreted as targets never to be exceeded, or as end-of-century targets. Recent literature proposes to move away from the latter, in favour of avoiding a temperature overshoot and ...
Kaj-Ivar van der Wijst, Andries F Hof, Detlef P van Vuuren   +2 more
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Problem Based Learning (PBL) Effectivenessless in Improving Critical Thinking Ability: Meta-Analysis Study

Guidena, 2021
This meta-analysis research aims to see the effectiveness of problem-based learning (PBL) to increase critical thinking skills. The study involved 20 research journals with 1386 participants.
Olivia Vecolitha, Ananta Yudiarso
doaj   +1 more source

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

Advanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken, Paula Beltran Lobo, Yunzhao Wu, Lyla A. Rowe, Emre Fertan, Cara L. Croft, Maria Jimenez‐Sanchez, Dezerae Cox, David Klenerman   +8 more
wiley   +1 more source

Chiral peptidoglycan mimics target bacterial wall biosynthesis for pathogen intervention

Nature Communications
The global burden of microbial infections and antimicrobial resistance, coupled with the absence of precise bacterial recognition modalities, demands innovative breakthroughs in antibacterial treatment.
Kefurong Deng, Dongzhe Zou, Zenan Zeng, Beiling Guo, Wensheng Gong, Yini Xu, Yachao Li, Xianghui Xu   +7 more
doaj   +1 more source

Large Language Model‐Based Chatbots in Higher Education

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of large language models (LLMs) in higher education can facilitate personalized learning experiences, advance asynchronized learning, and support instructors, students, and researchers across diverse fields. The development of regulations and guidelines that address ethical and legal issues is essential to ensure safe and responsible adaptation
Defne Yigci, Merve Eryilmaz, Ail K. Yetisen, Savas Tasoglu, Aydogan Ozcan   +4 more
wiley   +1 more source

Limites e possibilidade do Problem Based Learning (PBL) na formação do fisioterapeuta [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Programa de Pós-Graduação em Educação Científica e Tecnológica, Florianópolis, 2014.A atuação docente tanto no Brasil quanto em Portugal necessita de mudanças de paradigmas quanto aos modelos ...
Chesani, Fabíola Hermes
core  

Facilitating Postformal Thinking Through Problem-Based Learning in the History Survey Course: An Empirically Tested PBL Model [PDF]

, 2022
This case study presents a problem-based learning (PBL) model that guides general education history students to practice and acquire more advanced problem-solving skills – those found in postformal thinking systems – and to apply these thinking skills to
Charles Wynn, Wynn, Charles
core   +1 more source

Paris targets within reach by aligning, broadening and strengthening net-zero pledges

Communications Earth & Environment
Many countries have recently announced the ambition to reach net-zero emissions targets. Here we explore the climate and energy transition impacts of the following strategies using the IMAGE integrated assessment model: 1) implementing the pledged 2030 ...
Ioannis Dafnomilis, Michel den Elzen, Detlef van Vuuren   +2 more
doaj   +1 more source

Production of 3D printed biomodels of the canine brain for veterinary neuroanatomy teaching

Anatomical Sciences Education, EarlyView.
Abstract Teaching neuroanatomy presents multiple challenges to both students and teachers, as it is a subject with highly dense content that commonly causes the development of aversion by students, a phenomenon referred to as “neurophobia,” which has been documented in human and veterinary medicine students.
João Victor Barbosa Tenório Fireman, Antônio Chaves de Assis Neto   +1 more
wiley   +1 more source