Results 31 to 40 of about 5,057 (134)

Micro‐ultrasonography‐ vs MRI‐targeted biopsy in prostate cancer: Updated systematic review and meta‐analysis

BJU International, EarlyView.
Objective To refine prostate cancer (PCa) pathways by comparing micro‐ultrasonography‐targeted biopsy (micro‐US‐TBx) with magnetic resonance imaging (MRI)‐TBx for detecting clinically significant PCa (csPCa) and by evaluating diagnostic accuracy (sensitivity, specificity, positive predictive value, negative predictive value).
José Pedro Cassemiro Micheleto, Tallys Ávila Suzuki, Lucas Amorim Santos, Luann Porpino Sales, Roberto Iglesias Lopes, Bárbara Miranda Martins, Bárbara Vieira Lima Aguiar Melão, Mauricio Dener Cordeiro, Walid Sharour, Walid Shabana, William Carlos Nahas, Leopoldo Alves Ribeiro Filho, Caio Vinicius Suartz   +12 more
wiley   +1 more source

Unlocking Urban Climate Change Analysis in Global Kilometer‐Scale Climate Simulations

Geophysical Research Letters, Volume 53, Issue 13, 16 July 2026.
Abstract Coupled multi‐decadal global km‐scale simulations completed in recent years open new perspectives in the investigation and understanding of urban climate change. This study introduces a generic method for extracting urban areas and their rural references worldwide and validates it on hourly timescales with remote‐sensing observations of land ...
Xabier Pedruzo‐Bagazgoitia, Birgit Sützl, Emanuel Dutra, Joe McNorton, Aristofanis Tsiringakis, Christoph Rüdiger   +5 more
wiley   +1 more source

Multiple myeloma: A tale of deregulated transcription factors

HemaSphere, Volume 10, Issue 7, July 2026.
Abstract A comprehensive understanding of the molecular mechanisms underlying multiple myeloma (MM) pathogenesis is essential for developing therapeutic strategies that overcome disease heterogeneity and treatment relapse. In this review, we focus on transcription factors (TFs), key regulators of gene expression that play critical roles in normal ...
Nahia Gómez‐Echarte, Edurne San José‐Enériz, Estíbaliz Urizar‐Compains, Paula Rodriguez‐Otero, Felipe Prósper, Xabier Agirre   +5 more
wiley   +1 more source

STING Modulating ER‐Phagy in the Prelimbic Cortex Neurons Contributed to Neuropathic Pain and Emotional Comorbidity

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
SNL induced ER‐phagy impairment and ER stress increase in the PrL neuron via STING and the STING pathway. Our data indicated that enhancing ER‐phagy in PrL neurons might provide analgesic and antidepressant effects through STING and its pathways in SNL mice. ABSTRACT Background Our previous data suggested that autophagy is crucial for neuropathic pain.
Yongda Liu, Xu Yang, Shihui Kuai, Xi Chen, Zhibin Wang, Zhongsheng Yang, Xiaochuan Guo, Xin He, Ping Zhao   +8 more
wiley   +1 more source

OMIP‐121: Immune Phenotyping of Canine Peripheral Leukocytes by Mass Cytometry

Cytometry Part A, Volume 109, Issue 6, Page 393-412, June 2026.
ABSTRACT Dogs are a critical non‐rodent species used in preclinical safety studies, particularly, in the pharmaceutical field, due to their physiological, metabolic, and immunological similarities to humans. As such, immunophenotyping of canine peripheral blood mononuclear cells (PBMCs) plays a crucial role in translational research, immune monitoring,
Huyen Thuc Tran Luong, Dominique Revets, Sofie Vercammen, Ario de Marco, Hilde de Rooster, Antonio Cosma   +5 more
wiley   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, Volume 2, Issue 2, Page 309-342, June 2026.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Antibiotic Prophylaxis in Prostate Biopsies: Contemporary Practice Patterns in Germany

Frontiers in Surgery, 2018
PurposeProstate biopsy (pbx) is the most common outpatient procedure in urology. Complications are urinary tract infections, including hospitalization and sepsis.
Katharina Boehm, Fabian P. Siegel, Laila Schneidewind, Jennifer Kranz, Philipp Spachmann, Tanja Frank, Nina Huck, Florian Imkamp, Alexandre Pelzer   +8 more
doaj   +1 more source

Critical Review of Brazil Disk Techniques for Tensile Strength Characterization With an Emphasis on High Explosive Materials

Propellants, Explosives, Pyrotechnics, Volume 51, Issue 6, Page 862-875, June 2026.
ABSTRACT Mechanical properties are a critical performance metric for many high explosive (HE) materials and tensile strength properties are particularly important. Direct tensile measurements using dogbone shaped samples are the gold standard but they have the disadvantage that they are fairly large and require samples machined from billets.
Paul B. Mirkarimi
wiley   +1 more source

Clinical value of core length in contemporary multicore prostate biopsy. [PDF]

PLoS ONE, 2015
There is little data about the clinical value of core length for prostate biopsy (PBx). We investigated the clinical values of various clinicopathological biopsy-related parameters, including core length, in the contemporary multi-core PBx.Medical ...
Sangchul Lee, Seong Jin Jeong, Sung Il Hwang, Sung Kyu Hong, Hak Jong Lee, Seok Soo Byun, Gheeyoung Choe, Sang Eun Lee   +7 more
doaj   +1 more source

Tírala Plena: findings from the formative research to inform the initiative “Reaching those most left behind through comprehensive sexuality education for out-of-school young people” in Colombia

Sexual and Reproductive Health Matters, 2023
This paper presents the results of formative research conducted from January to June 2020 in the Department of Atlántico, Caribbean region of Colombia, whose findings were used as inputs to design the national strategy for comprehensive sexuality ...
Jair Vega Casanova, Johanna Blanco, Natalia Buitrago Rovira, Diana Matilde Pulido Jaramillo, Karen Adrians Pacheco, Alma Virginia Camacho-Hubner   +5 more
doaj   +1 more source