Results 71 to 80 of about 601,144 (294)

Assessment of variation in rice maintainer lines using principal component analysis

Electronic Journal of Plant Breeding
The aim of this study was to explore the characteristics essential for a maintainer line to effectively complement the A lines in hybrid rice production.
B. Edukondalu1, V. Ram Reddy1, T. Shobha Rani1, CH. Aruna Kumari2 and B. Soundharya3
doaj   +1 more source

Analytical method development of pitavastatin-loaded SNEDDS formulation: Multivariate analysis regarding ultraviolet spectrophotometry analysis

Journal of Food and Pharmaceutical Sciences, 2019
Herein, this work aimed to develop and assess feasibility of multivariate model of partial least square analysis for specific quantification of pitavastatin (PVT)-loaded self-nano emulsion (SNE) formulation using UV Vis spectrophotometry. PVT loaded into
Kuncahyo I, Choiri S, Fudholi A, Abdul Rohman, Ronny Martien   +4 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Le fait du prince comme cause d’admission au régime de force majeure en droit minier congolais : notion, portée et implications [PDF]

Mouvements et Enjeux Sociaux
La succession d’évènements tragiques au cours des XX et XXIe siècles a mis en évidence l’importance de la gestion des risques avec notamment des risques industriels, financiers, sociétaux (les soulèvements), sanitaires (pandémie de covid-19), ou encore ...
Patrick BONDONGA LESAMBO , Kevin ESHIMATA NGIMBI   +1 more
doaj  

Dimensionality Reduction and Classification of Dermatological Images using PCA and Machine Learning [PDF]

EPJ Web of Conferences
Skin diseases pose grave diagnosis issues since they are highly similar among classes and have varied patterns over the various skin colors, particularly in Indian subjects. The current work proposes a mixed strategy using transfer learning-based feature
Surwadkar Tushar, Deshmukh Sujata
doaj   +1 more source

martaajarzyna/PCA-ForAnalysisOfBiodiversityChange: First release of PCA for biodiversity assessments (Jarzyna and Stagge)

, 2022
This is the code for using Principal Component Analysis (PCA) for assessments of change in multiple facets of biodiversity (manuscript in review by Jarzyna and Stagge)
Marta Jarzyna
core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source