Results 11 to 20 of about 182 (129)

ST6GAL1‐mediated aberrant sialylation promotes prostate cancer progression

open access: yesThe Journal of Pathology, Volume 261, Issue 1, Page 71-84, September 2023., 2023
Abstract Aberrant glycosylation is a universal feature of cancer cells, and cancer‐associated glycans have been detected in virtually every cancer type. A common change in tumour cell glycosylation is an increase in α2,6 sialylation of N‐glycans, a modification driven by the sialyltransferase ST6GAL1.
Emma Scott   +41 more
wiley   +1 more source

Turning SKD 11 Hardened Steel: An Experimental Study of Surface Roughness and Material Removal Rate Using Taguchi Method

open access: yesAdvances in Materials Science and Engineering, Volume 2023, Issue 1, 2023., 2023
Heat‐treated steel is widely used in industrial applications due to its high strength and other desirable mechanical qualities. Grinding, which requires a lot of power and is expensive, is typically used to harden machining. In recent times, hard machining has emerged as a viable alternative to grind in select applications.
Shah Ashiquzzaman Nipu   +7 more
wiley   +1 more source

Effect of ZrB2 Particles on Machining Parameters of AA7475 Alloy‐Based Composites by Optimization Technique

open access: yesAdvances in Materials Science and Engineering, Volume 2023, Issue 1, 2023., 2023
ZrB2 particle‐reinforced AA7475 is a potential material for high‐performance aeronautical engine blades because of its exceptional characteristics. The machinability of ZrB2/AA7475 metal matrix composites (MMC) is still a challenge because of the influence of ZrB2 particles.
C. R. Mahesha   +9 more
wiley   +1 more source

The effect of hydrogen on the fracture toughness of friction‐stir welded API 5L X70 pipeline steels

open access: yesFatigue &Fracture of Engineering Materials &Structures, Volume 45, Issue 10, Page 3009-3024, October 2022., 2022
Abstract The hydrogen embrittlement (HE) leads to severe steel degradation of mechanical properties. The hydrogen atoms diffuse into the steel and get positioned into reversible and irreversible trap sites. The pipe to transport oil and gas needs to be welded to construct long‐distance pipeline projects; thus, friction‐stir welding (FSW) has proven an ...
Joseane M. Giarola   +5 more
wiley   +1 more source

The prostate tissue‐based telomere biomarker as a prognostic tool for metastasis and death from prostate cancer after prostatectomy

open access: yesThe Journal of Pathology: Clinical Research, Volume 8, Issue 5, Page 481-491, September 2022., 2022
Abstract Current biomarkers are inadequate prognostic predictors in localized prostate cancer making treatment decision‐making challenging. Previously, we observed that the combination of more variable telomere length among prostate cancer cells and shorter telomere length in prostate cancer‐associated stromal cells – the telomere biomarker – is ...
Christopher M Heaphy   +13 more
wiley   +1 more source

A Contemporary Review on Friction Stir Welding of Circular Pipe Joints and the Influence of Fixtures on This Process

open access: yesAdvances in Materials Science and Engineering, Volume 2022, Issue 1, 2022., 2022
The permanent metal joining processes play a vital role in assembling the complex aluminium structures of the aerospace, automotive, marine, and oil industries. The invention of friction stir welding (FSW) redefined the mechanism of metal joining to produce high‐quality welds by eliminating the consumption of electrodes and shielding gases, resulting ...
S. M. Senthil   +3 more
wiley   +1 more source

A Survey of Machine Learning in Friction Stir Welding, including Unresolved Issues and Future Research Directions

open access: yesMaterial Design &Processing Communication, Volume 2022, Issue 1, 2022., 2022
Friction stir welding is a method used to weld together materials considered challenging by fusion welding. FSW is primarily a solid phase method that has been proven efficient due to its ability to manufacture low‐cost, low‐distortion welds. The quality of weld and stresses can be determined by calculating the amount of heat transferred.
Utkarsh Chadha   +13 more
wiley   +1 more source

Optimization of Surface Quality and Power Consumption in Machining Hardened AISI 4340 Steel

open access: yesAdvances in Materials Science and Engineering, Volume 2022, Issue 1, 2022., 2022
Hard turning has become an attractive method of machining for most manufacturers in the last few years due to its low cost and superior surface quality compared to grinding. In this experimental study, the machinability of hardened steel under dry machining on a CNC lathe is undertaken to optimize the cutting parameters for minimum surface roughness ...
Dennis Ochengo   +4 more
wiley   +1 more source

Influence of Friction Stir Welding Process on the Mechanical Characteristics of the Hybrid Joints AA2198‐T8 to AA2024‐T3

open access: yesAdvances in Materials Science and Engineering, Volume 2022, Issue 1, 2022., 2022
The study presents the hybrid joining of the third generation AA2198‐T8 aluminum lithium alloy to AA2024‐T3 aluminum copper alloy, which has been highly demanded recently in the aerospace industry. This investigation aims to reduce the cost of production in the industrial sector.
Ahmed Samir Anwar Alemdar   +3 more
wiley   +1 more source

Optimization of Plasma Arc Cutting Parameters on Machining of Inconel 718 Superalloy

open access: yesJournal of Nanomaterials, Volume 2022, Issue 1, 2022., 2022
Nickel‐based super composites are widely applied in the industry. These alloys withstand high thermal debility conditions and give better strength to machine parts in aviation, biomechanical, marine, and vehicle commerce. Nickel‐based alloys have high quality, corrosion resistance, and high heat refusal.
M. Karthick   +6 more
wiley   +1 more source

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