Results 201 to 210 of about 142,502 (333)
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber +12 more
wiley +1 more source
Visceral adiposity and insulin resistance in polycystic ovarian syndrome - A cross-sectional, observational study. [PDF]
Sridharan A +7 more
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy +8 more
wiley +1 more source
Opportunities to improve the care of individuals with polycystic ovary syndrome in Canada: Systematic review. [PDF]
Patrick H +6 more
europepmc +1 more source
Aberrant DNMTs Promote TXNIP Upregulation and Ovarian Fibrosis in PCOS. [PDF]
In a rat model of DHEA/DHT‐induced PCOS and in granulosa cells (GCs), upregulated DNMT1, DNMT3A, and DNMT3B inhibit TXNIP degradation, leading to TXNIP accumulation, which drives ovarian fibrosis and tissue injury. ABSTRACT Hyperandrogenism and elevated thioredoxin‐interacting protein (TXNIP) are potential causes of infertility in women with polycystic
Weng Y +12 more
europepmc +2 more sources
Molecular profiles and outcomes of CR rate in 74 cases. ABSTRACT Objective To investigate the impact of various molecular characteristics on the outcomes of fertility‐preserving therapy in patients with endometrial cancer (EC) and atypical endometrial hyperplasia (AEH).
Xue‐Qian Qian +4 more
wiley +1 more source
Outcome-specific shifts in homocysteine-androgen correlations in polycystic ovary syndrome. [PDF]
Han Q, Zhao J, Li M, Xin M, Yin X, He J.
europepmc +1 more source
This review evaluates the available pharmacokinetic data on the plasma‐to‐breastmilk transfer of first‐ and second‐line T2DM drugs against available clinical guideline recommendations. A list of drug therapies for treating T2DM was generated from national and international clinical guidelines.
Katherine Richardson +4 more
wiley +1 more source
Are serum MOTS-c levels and MOTS-c m.1382A>C polymorphism related to polycystic ovary syndrome? [PDF]
Filibeli BE +7 more
europepmc +1 more source

