Results 61 to 70 of about 72,666 (311)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Cr(II) and Cr(I) PCP Pincer Complexes: Synthesis, Structure, and Catalytic Reactivity

, 2019
We report the synthesis of the square-planar Cr(II) PCP complex [Cr(POCOP-tBu)(Br)] which is a valuable precursor for novel chromium borohydride PCP pincer complexes in formal oxidation states +I and ...
Karl, Kirchner, Daniel, Himmelbauer, Marc, Pignitter, Luis F., Veiros, Berthold, Stöger   +4 more
core   +1 more source

Measurements of induced vibrations due to steel pipe pile driving in Al-Fao soil: Effect of partial end closure

Open Engineering
The experimental study investigated the impact of partially closing the end of a tubular steel pile with a diameter of 1.22 m on the induced driving vibrations.
Saher Hamed S., Al-Jubair Haider S., Ali Jaafar K.   +2 more
doaj   +1 more source

Diagnosis of Pneumocystis pneumonia by real-time PCR in patients with various underlying diseases

Journal of Microbiology, Immunology and Infection, 2020
Background: Pneumocystis pneumonia (PCP) is a disease caused by the opportunistic infection of the fungus Pneumocystis jirovecii. Several PCR methods have been developed to aid in the diagnosis of PCP.
Shu-Li Yang, Ying-Hao Wen, Yu-Shan Wu, Mei-Chia Wang, Pi-Yueh Chang, Shuan Yang, Jang-Jih Lu   +6 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Dinuclear PCP pincer complexes from Lewis acidic [Pd(OTf)(PCP)] and basic [Pd(4-Spy)(PCP)] (OTf = triflate; 4-Spy = 4-pyridinethiolate; PCP = –CH(CH₂CH₂PPh₂)₂)

, 2007
The Lewis acidic pincer with a labile triflate ligand, viz. [Pd(OTf)(PCP)] (PCP = –CH(CH₂CH₂PPh₂)₂) 1 was prepared from [PdCl(PCP)] with AgOTf.
Hor, T.S.A., Huynh, H.V., Hor, T.S. Andy, Neo, K.E., Koh, Lip Lin, Hor, T. S Andy, Henderson, W., Neo, Kian Eang, Henderson, William, Koh, L.L., Huynh, Han Vinh   +10 more
core   +1 more source

Coagulation disorders in myocardial infarction with nonobstructive coronary arteries

Рациональная фармакотерапия в кардиологии
Aim. To investigate the state of the platelet and plasma components of hemostasis in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA).Material and methods.
A. S. Pisaryuk, A. A. Filkova, E. S. Tukhsanboev, G. S. Svidelskaya, A. A. Ignatova, E. A. Ponomarenko, A. A. Martyanov, A. A. Tarakanova, I. A. Meray, M. A. Panteleev, A. N. Sveshnikova, Z. D. Kobalava   +11 more
doaj   +1 more source

Epidemiology of Pneumocystis jirovecii Pneumonia and (Non-)use of Prophylaxis

Frontiers in Cellular and Infection Microbiology, 2020
Objectives:Pneumocystis jirovecii pneumonia (PCP) is an AIDS-defining illness. In patients with HIV, the benefit of PCP prophylaxis is well-defined when the CD4 T-cell count decreases below 200 cells/μL.
Albert Dunbar, Alexander Schauwvlieghe, Alexander Schauwvlieghe, Alexander Schauwvlieghe, Sheruna Algoe, Jaap J. van Hellemond, Marijke Reynders, Stefaan Vandecasteele, Jerina Boelens, Pieter Depuydt, Bart Rijnders   +10 more
doaj   +1 more source

Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven, N. Satyadev, A. E. M. Bastiaansen, Y. D. Piura, J. Kerstens, Y. S. Crijnen, J. Brenner, T. Brand, T. M. Bienfait, S. Veenbergen, J. M. de Vries, F. J. de Jong, E. G. P. Dopper, P. A. E. Sillevis Smitt, H. Seelaar, G. S. Day, M. J. Titulaer   +16 more
wiley   +1 more source

ARE THERE DIFFERENCES IN STATIN PRESCRIBING PRACTICES BASED ON PROVIDER AND PATIENT GENDERS?  A RETROSPECTIVE, QUANTITATIVE AND QUALITATIVE CHART REVIEW

American Journal of Preventive Cardiology, 2021
Payton Skawinski, Ali Philander, Nick Moy   +2 more
doaj   +1 more source